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27221

Acetic acid

glacial, puriss., 99-100%

Synonym(s):

Glacial acetic acid

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1 L

Estimated to ship onJuly 27, 2026fromMILWAUKEE

$1,087.50

About This Item

Linear Formula:
CH3CO2H
CAS Number:
64-19-7
Molecular Weight:
60.05
UNSPSC Code:
12352106
NACRES:
NA.21
PubChem Substance ID:
329752985
EC Number:
200-580-7
Beilstein/REAXYS Number:
506007
MDL number:
MFCD00036152
Assay:
99-100%
Form:
liquid

$1,087.50

List Price$1450.00Save 25%

Estimated to ship onJuly 27, 2026Details

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vapor density

2.07 (vs air)

Quality Segment

100

grade

puriss.

assay

99-100%

form

liquid

autoignition temp.

800 °F

expl. lim.

16 %, 92 °F, 4 %, 59 °F

technique(s)

mass spectrometry (MS): suitable

impurities

≤0.0005% heavy metals (as Pb), ≤0.005% non-volatile matter

refractive index

n20/D 1.371 (lit.)

pH

2.5 (20 °C, 50 g/L)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

density

1.04 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤5 mg/kg, sulfate (SO42-): ≤5 mg/kg

cation traces

Fe: ≤5 mg/kg

SMILES string

[F2C(F2C)13F3C]C(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

General description

Acetic acid is an organic carboxylic acid. It is a hygroscopic liquid having pungent odor. Its anhydrous form is commonly referred as glacial acetic acid. It forms dimers linked by hydrogen bonds in solution and gaseous phases. It is weakly acidic in nature.

Application

Acetic acid is widely employed as solvent for various oxidation reactions. It has been used in the analysis of synthetic peptides by electron transfer dissociation (ETD) tandem mass spectrometry (MS/MS).[1] It may be used in the preparation of peroxyacetic acid (disinfectant), via reaction with perhydrol (30% hydrogen peroxide).

Other Notes

The article number 27221-6X1L will be discontinued. Please order the single bottle 27221-1L which is physically identical with the same exact specifications.

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This Item
27225695092W200611
Acetic acid glacial, puriss., 99-100%

Sigma-Aldrich

27221

Acetic acid

Acetic acid glacial, puriss., meets analytical specification of Ph. Eur., BP, USP, 99.8-100.5%

Sigma-Aldrich

27225

Acetic acid

Acetic acid glacial, ACS reagent, ≥99.7%

Sigma-Aldrich

695092

Acetic acid

Acetic acid ≥99.5%, FCC, FG

Sigma-Aldrich

W200611

Acetic acid

description

glacial, puriss., 99-100%

description

glacial, puriss., meets analytical specification of Ph. Eur., BP, USP, 99.8-100.5%

description

glacial, ACS reagent, ≥99.7%

description

≥99.5%, FCC, FG

grade

puriss.

grade

puriss.

grade

-

grade

-

assay

99-100%

assay

99.8-100.5%

assay

≥99.7%

assay

≥99.5%

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

300, 400

form

liquid

form

liquid

form

liquid

form

liquid

pH

2.5 (20 °C, 50 g/L)

pH

2.5 (20 °C, 50 g/L)

pH

2.5 (20 °C, 50 g/L)

pH

2.5 (20 °C, 50 g/L)

cation traces

Fe: ≤5 mg/kg

cation traces

Al: ≤0.5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤2 mg/kg, Pb: ≤0.5 mg/kg, Zn: ≤5 mg/kg

cation traces

Fe: ≤0.2 ppm, heavy metals: ≤0.5 ppm (by ICP)

cation traces

As: ≤3 ppm, Cd: ≤1 ppm, Hg: ≤1 ppm, heavy metals (as Pb): ≤0.5 ppm

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pictograms

FlameCorrosion
GHS02,GHS05

signalword

Danger

hcodes

H226,H314

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

102.2 °F - closed cup

flash_point_c

39 °C - closed cup

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Questions

  1. Which ascidic acid is best fro extraction buffers?

    1 answer

    1. Extraction buffers are typically used for sample preparation. One would probably want to use a high-purity (> 99 %) acetic acid that has also been tested to make sure that it is low in common impurities. Product 27221 or Product 338826 are relatively reasonable for application.

      Please see the product below:
      https://www.sigmaaldrich.com/product/sigald/338826

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