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MilliporeSigma

320552

Toluene

ACS reagent, ≥99.5%

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1 L

$96.40

4 X 4 L

$738.00

$96.40


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About This Item

Linear Formula:
C6H5CH3
CAS Number:
Molecular Weight:
92.14
Beilstein/REAXYS Number:
635760
EC Number:
MDL number:
UNSPSC Code:
12352002
PubChem Substance ID:
NACRES:
NA.21
Grade:
ACS reagent
Assay:
≥99.5%
Bp:
110-111 °C (lit.)
Vapor pressure:
22 mmHg ( 20 °C)
26 mmHg ( 25 °C)

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grade

ACS reagent

agency

suitable for EPA 1613

vapor density

3.2 (vs air)

vapor pressure

22 mmHg ( 20 °C)
26 mmHg ( 25 °C)

assay

≥99.5%

form

liquid

autoignition temp.

997 °F

expl. lim.

7 %

dilution

(for analytical testing)

impurities

H2SO4, passes test (darkened)
≤0.003% S compounds
≤0.03% water

evapn. residue

≤0.001%

color

APHA: ≤10

refractive index

n/D 1.496 (lit.)

bp

110-111 °C (lit.)

mp

-93 °C (lit.)

density

0.865 g/mL at 25 °C (lit.)

SMILES string

Cc1ccccc1

InChI

1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3

InChI key

YXFVVABEGXRONW-UHFFFAOYSA-N

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1 of 4

This Item
67675617996532249
grade

ACS reagent

grade

ACS reagent

grade

Laboratory Reagent

grade

ACS reagent, puriss. p.a.

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

assay

≥99.5%

assay

≥99.5%

assay

≥99.3%

assay

≥99.7% (GC)

form

liquid

form

liquid

form

liquid

form

liquid

impurities

H2SO4, passes test (darkened), ≤0.03% water, ≤0.003% S compounds

impurities

H2SO4, passes test (darkened), ≤0.003% S compounds, ≤0.03% Water

impurities

≤0.05% water

impurities

≤0.0001% thiophene, ≤0.001% free acid (as HCl), ≤0.001% free alkali (as NaOH), ≤0.001% non-volatile matter, ≤0.003% S-compounds (as S), ≤0.02% water (Karl Fischer)

refractive index

n/D 1.496 (lit.)

refractive index

n/D 1.496 (lit.)

refractive index

n/D 1.496 (lit.)

refractive index

n/D 1.496 (lit.), n20/D 1.496-1.498

General description

Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.

Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.

Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.

Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.

Application

Toluene can be used as a solvent:
  • To synthesize azines from alcohols and hydrazine hydrate[1].
  • In the lipase-catalyzed synthesis of epoxy-functionalized polyesters via polycondensation[2].

signalword

Danger

Hazard Classifications

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

39.9 °F - closed cup

flash_point_c

4.4 °C - closed cup


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Convenient synthesis of symmetrical azines from alcohols and hydrazine catalyzed by ruthenium (II) hydrazone complex in air
Gayathri S, et al.
Inorganica chimica acta, 120957, 537-537 (2022)
Lipase-catalyzed synthesis of an epoxy-functionalized polyester from the suberin monomer cis-9,10-epoxy-18-hydroxyoctadecanoic acid.
Ann Olsson et al.
Biomacromolecules, 8(2), 757-760 (2007-01-25)
Marina Shalaeva et al.
Journal of medicinal chemistry, 56(12), 4870-4879 (2013-05-29)
This study demonstrates that ΔlogP(oct-tol) (difference between logP(octanol) and logP(toluene)) describes compounds propensity to form intramolecular hydrogen bonds (IMHB) and may be considered a privileged molecular descriptor for use in drug discovery and for prediction of IMHB in drug candidates.
Murat Yücel et al.
Neuroscience and biobehavioral reviews, 32(5), 910-926 (2008-05-06)
Organic solvent abuse is associated with increased risk for serious medical, neurological, and neuropsychological impairments. While animal research suggests that exposure to organic solvents (especially toluene) may be neurotoxic, much less is known about the consequences of long-term exposure in
Perrine Hoet et al.
Critical reviews in toxicology, 38(2), 127-170 (2008-02-09)
Noise is the most common preventable cause of irreversible sensorineural hearing loss. During recent years, the results of experimental and human investigations have raised the level of concern about the potential ototoxicity of chemical agents and their interaction with noise.

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This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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