360481

Sigma-Aldrich

1,4-Dioxane

ACS reagent, ≥99.0%

Synonym(s):
Diethylene oxide, Dioxane
Empirical Formula (Hill Notation):
C4H8O2
CAS Number:
Molecular Weight:
88.11
Beilstein/REAXYS Number:
102551
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

ACS reagent

vapor density

3 (vs air)

vapor pressure

27 mmHg ( 20 °C)
40 mmHg ( 25 °C)

assay

≥99.0%

form

liquid

autoignition temp.

356 °F

expl. lim.

22 %

impurities

≤0.0016 meq/g Titr. acid
≤0.005% Peroxide (as H2O2)
≤0.01% Carbonyl (as HCHO)
≤0.05% water

evapn. residue

≤0.005%

color

APHA: ≤20

refractive index

n20/D 1.422 (lit.)

pH

6.0-8 (20 °C, 500 g/L)

bp

100-102 °C (lit.)

mp

10-12 °C (lit.)

transition temp

freezing point ≥11.0

density

1.034 g/mL at 25 °C (lit.)

SMILES string

C1COCCO1

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Statements

Target Organs

Respiratory system

Supp Hazards

EUH019 - EUH066

RIDADR

UN1165 - class 3 - PG 2 - Dioxane

WGK Germany

WGK 2

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11 °C - closed cup

Certificate of Analysis

Certificate of Origin

Self-curable benzoxazine functional polybutadienes synthesized by click chemistry.
Kukut M, et al.
Designed Monomers and Polymers, 12(2), 167-176 (2009)
Oxidation and biodegradability enhancement of 1,4-dioxane using hydrogen peroxide and ozone.
C D Adams et al.
Environmental science & technology, 28(11), 1812-1818 (1994-10-01)
Alkene trifluoromethylation coupled with C-C bond formation: construction of trifluoromethylated carbocycles and heterocycles.
Hiromichi Egami et al.
Angewandte Chemie (International ed. in English), 52(14), 4000-4003 (2013-02-27)
Christof Aellig et al.
ChemSusChem, 5(9), 1737-1742 (2012-07-05)
The dehydration of D-fructose to 5-hydroxymethylfurfural was studied under single-phase conditions in the low boiling solvent 1,4-dioxane at moderate temperatures in the presence of the solid acid-catalyst Amberlyst-15. The reaction was first examined and optimized under batch conditions, where it...
Kiyoaki Ishimoto et al.
Biomacromolecules, 13(11), 3757-3768 (2012-09-19)
For developing broader application of biobased polymers, graft copolymers and comb polymers having poly(lactic acid) (PLA) side chains have been synthesized by using a macromonomer technique. PLA macromonomers (MMm) having a methacryloyl polymerizable group with different PLA chain length with...

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