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360589
Tetrahydrofuran
≥99.0%, ACS reagent, contains 200-400 ppm BHT as inhibitor
Synonym(s):
THF, Butylene oxide, Oxolane, Tetramethylene oxide
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| Size/SKU | Availability | Price |
|---|---|---|
500 mL | Available to ship TODAYfromMILWAUKEE | $118.00 |
1 L | Available to ship TODAYfromMILWAUKEE | $160.00 |
Estimated to ship onSeptember 17, 2026fromMILWAUKEE. | $217.00 | |
2.5 L | Available to ship TODAYfromMILWAUKEE | $280.00 |
4 L | Available to ship TODAYfromMILWAUKEE | $392.00 |
Estimated to ship onNovember 04, 2026fromMILWAUKEE. | $509.00 | |
6 x 500 mL | Available to ship TODAYfromMILWAUKEE | $600.00 |
6 x 1 L | Available to ship TODAYfromMILWAUKEE | $789.00 |
18 L | Available to ship TODAYfromMILWAUKEE | $980.00 |
4 x 4 L | Available to ship TODAYfromMILWAUKEE | $1,320.00 |
Check Cart for Availability | $4,700.00 |
About This Item
$118.00
Available to ship TODAYDetails
Product Name
Tetrahydrofuran, contains 200-400 ppm BHT as inhibitor, ACS reagent, ≥99.0%
grade
ACS reagent
Quality Segment
vapor density
2.5 (vs air)
vapor pressure
114 mmHg ( 15 °C), 143 mmHg ( 20 °C)
assay
≥99.0%
form
liquid
autoignition temp.
610 °F
contains
200-400 ppm BHT as inhibitor
expl. lim.
1.8-11.8 %
technique(s)
HPLC: suitable
impurities
≤0.015% peroxide (as H2O2), ≤0.05% water
evapn. residue
≤0.03%
color
APHA: ≤20
refractive index
n20/D 1.407 (lit.)
pH
~7
bp
65-67 °C (lit.)
mp
−108 °C (lit.)
solubility
water: soluble
density
0.889 g/mL at 25 °C (lit.)
SMILES string
C1CCOC1
InChI
1S/C4H8O/c1-2-4-5-3-1/h1-4H2
InChI key
WYURNTSHIVDZCO-UHFFFAOYSA-N
General description
Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.
Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.
Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.
Application
- Organic synthesis
b) Organometallic compounds
c) Reformatsky
d) Lithiation
e) Hydride reduction
f) Metal-catalyzed coupling (Heck, Stile, Suzuki)
g) Lewis acid mediated reactions
- Crystallization
- Polymerization. Ex. RAFT (Reversible Addition-Fragmentation Chain Transfer) polymerization of p-acetoxystyrene
- Coatings
- As an O-donor ligand to form coordination complexes
- As mobile phase solvent in high-performance liquid chromatography
Features and Benefits
1 of 1
This Item | ||
|---|---|---|
| description contains 200-400 ppm BHT as inhibitor, ACS reagent, ≥99.0% | description anhydrous, ≥99.9%, inhibitor-free | description Pharmaceutical Secondary Standard; Certified Reference Material |
| technique(s) HPLC: suitable | technique(s) - | technique(s) - |
| grade ACS reagent | grade anhydrous | grade certified reference material, pharmaceutical secondary standard |
| Quality Level 200 | Quality Level 200 | Quality Level 300 |
| assay ≥99.0% | assay ≥99.9% | assay - |
| solubility water: soluble | solubility H2O: soluble | solubility - |
| form liquid | form liquid | form - |
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signalword
Danger
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
target_organs
Central nervous system, Respiratory system
supp_hazards
Storage Class
3 - Flammable liquids
flash_point_f
-6.2 °F - closed cup
flash_point_c
-21.2 °C - closed cup
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Why do peroxides form in certain solvents and how do I test for it?
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A significant number of laboratory solvents can undergo autoxidation under normal storage conditions to form unstable and potentially dangerous peroxide by-products. Molecular structure is the primary factor relating to a material’s potential for hazardous peroxide formation. It is important to understand the stability of materials in use and if unclear, consult Sigma-Aldrich Technical Support, techserv@sial.com.
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What apparatus do you recommend for HPLC solvent filtration?
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The Sigma-Aldrich Vacuum Filtration Assembly gives you all the components you need including: funnel top, fritted glass funnel support, filtration flask, aluminum clamp, and silicone stopper. The Acrodisc Syringe Filters offer high quality filtration for analytical samples, certified for HPLC to ensure low extractable and available in a broad range of membranes to meet sample compatibility requirements.
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Who do I contact about larger solvent volume needs?
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Email us at labessentials@sial.com or visit Sigma-Aldrich Fine Chemicals for development and manufacturing-scale inquiries: safcglobal@sial.com
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What are some of the preservatives used in the most common ethers and chlorinated solvents and why are they added?
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Certain solvents will degrade over time requiring special handling and storage considerations. In addition, the products of certain degradation processes pose a potential safety risk if present at sufficiently high levels. For these types of materials, small amounts of stabilizing chemicals are added to slow down or stop material degradation.
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What are the options for drying solvents?
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Sigma-Aldrich offers a full range of high-purity solvents with extremely low water levels specifically manufactured for moisture sensitive Organic and Biotech applications. Sigma-Aldrich also carries various drying agents such as molecular sieves, which are typically compatible with organic solvents.
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Can you recommend a Solvent Extractor for organics from aqueous solution?
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Solvent extractors are often used for the quantitative extraction of organics from aqueous solutions and separations in immunoassays. The MIXXOR system has been applied successfully in many laboratory solvent extraction operations and is ideal for the rapid screening of alternative solvents for specific extraction problems.
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