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419494

Sigma-Aldrich

Osmium tetroxide

ACS reagent, ≥98.0%

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Synonym(s):
Osmium(VIII)-oxide, ‘Osmic acid’
Linear Formula:
OsO4
CAS Number:
Molecular Weight:
254.23
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NB.24

grade

ACS reagent

Quality Level

vapor density

8.8 (vs air)

vapor pressure

7 mmHg ( 20 °C)

description

identification passes test

Assay

≥98.0%

form

crystalline

reaction suitability

reagent type: oxidant

clarity of soln

passes test

bp

130 °C (lit.)

mp

39.5-41 °C (lit.)

solubility

acetone: soluble(lit.)
carbon tetrachloride: soluble(lit.)
methyl tert-butyl ether: soluble(lit.)
toluene: soluble(lit.)
water: soluble(lit.)

storage temp.

2-8°C

SMILES string

O=[Os](=O)(=O)=O

InChI

1S/4O.Os

InChI key

VUVGYHUDAICLFK-UHFFFAOYSA-N

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This Item
O5500201030215465
Osmium tetroxide ACS reagent, ≥98.0%

Sigma-Aldrich

419494

Osmium tetroxide

Essential Grade
Osmium tetroxide Sealed ampule.

Sigma-Aldrich

O5500

Osmium tetroxide

-
Osmium tetroxide ReagentPlus®, 99.8%

Sigma-Aldrich

201030

Osmium tetroxide

-
Mercury(II) chloride ACS reagent, ≥99.5%

Sigma-Aldrich

215465

Mercury(II) chloride

-
vapor pressure

7 mmHg ( 20 °C)

vapor pressure

7 mmHg ( 20 °C)

vapor pressure

7 mmHg ( 20 °C)

vapor pressure

1.3 mmHg ( 236 °C)

assay

≥98.0%

assay

-

assay

99.8%

assay

≥99.5%

form

crystalline

form

powder

form

crystalline, powder

form

powder

mp

39.5-41 °C (lit.)

mp

39.5-41 °C (lit.)

mp

39.5-41 °C (lit.)

mp

277 °C (lit.)

solubility

acetone: soluble(lit.), carbon tetrachloride: soluble(lit.), methyl tert-butyl ether: soluble(lit.), toluene: soluble(lit.), water: soluble(lit.)

solubility

-

solubility

-

solubility

acetic acid: soluble(lit.), acetone: soluble in salt form(lit.), alcohol: soluble(lit.), diethyl ether: passes test, ethyl acetate: soluble(lit.), glycerol: soluble(lit.), water: soluble(lit.)

Application

Osmium tetroxide may be used in the following processes:
  • As a tissue-staining contrast agent for staining tissues.
  • Lactonization of alkenols to lactones by oxidation.
  • Synthesis of the corresponding tetrols from 1,5-cycloocatdiene by bishydroxylation.

Pictograms

CorrosionSkull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Customers Also Viewed

Slide 1 of 7

1 of 7

On the Stereoselectivity in Bisdihydroxylation of 1,5-cyclooctadiene with Osmium Tetroxide.
Kawazoe K, et al.
Synthetic Communications, 31(14), 2107-2112 (2001)
P Maupin-Szamier et al.
The Journal of cell biology, 77(3), 837-852 (1978-06-01)
We have studied the destruction of purified muscle actin filaments by osmium tetroxide (OsO4) to develop methods to preserve actin filaments during preparation for electron microscopy. Actin filaments are fragmented during exposure to OsO4. This causes the viscosity of solutions
The crystal structure of osmium tetroxide.
Ueki T, et al.
Acta Crystallographica, 19(2), 157-160 (1965)
Vacuum ultraviolet spectra of osmium tetroxide and ruthenium tetroxide.
Roebber JL, et al.
J. Chem. Phys. , 60(8), 3166-3173 (1974)
Direct Lactonization of Alkenols via Osmium Tetroxide-Mediated Oxidative Cleavage.
Schomaker JM, et al.
Organic Letters, 5(17), 3089-3092 (2003)

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