MilliporeSigma
All Photos(1)

494496

Sigma-Aldrich

1-Methyl-2-pyrrolidinone

biotech. grade, ≥99.7%

Synonym(s):
1-Methyl-2-pyrrolidone, N-Methyl-2-pyrrolidone, NMP
Empirical Formula (Hill Notation):
C5H9NO
CAS Number:
Molecular Weight:
99.13
Beilstein:
106420
EC Number:
MDL number:
PubChem Substance ID:

grade

biotech. grade

Quality Level

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

assay

≥99.7%

form

liquid

autoignition temp.

518 °F

expl. lim.

9.5 %

impurities

≤0.005% water
≤0.01% free amines (CH3NH2)

color

APHA: ≤20

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

solubility

acetone: miscible(lit.)
alcohol: miscible(lit.)
chloroform: miscible(lit.)
ethyl acetate: miscible(lit.)
water: miscible(lit.)

density

1.028 g/mL at 25 °C (lit.)

λ

H2O reference

UV absorption

λ: 285 nm Amax: 1.00
λ: 300 nm Amax: 0.50
λ: 325 nm Amax: 0.10
λ: 350-400 nm Amax: 0.01

application(s)

peptide synthesis

SMILES string

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

N-Methyl-2-pyrrolidinone (N-methylpyrrolidone, NMP) is a polar cyclic organic solvent. A study on the impact of NMP on Saccharomyces cerevisiae revealed that it induced aneuploidy. Characteristic properties of NMP include low viscosity, excellent dissolving power and enhanced demulsifying property. It is a better alternative to phenol in selectively treating lube feedstock. The behavior of fullerene-C60 in NMP solution has been examined based on electronic absorption and photoluminescence spectral data. A solution of sodium borohydride (NaBH4) in NMP showed increased reactivity towards debromination of alkyl bromide. The enhanced selectivity of NMP-ethylene glycol solvent mixture for aromatic hydrocarbon extraction has been analyzed by gas chromatography.

Packaging

1, 2, 4×2 L in Sure/Seal™

Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

195.8 °F - Pensky-Martens closed cup

Flash Point(C)

91 °C - Pensky-Martens closed cup

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service