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496219

N,N-Diisopropylethylamine

99.5%, biotech. grade

Synonym(s):

N-Ethyldiisopropylamine, DIPEA, Ethyldiisopropylamine, Hünig’s base

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Size/SKUAvailabilityPrice
100 mL
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$114.00
2 L
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$1,170.00

About This Item

Linear Formula:
[(CH3)2CH]2NC2H5
CAS Number:
Molecular Weight:
129.24
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
230-392-0
MDL number:
eCl@ss:
32150312
Assay:
99.5%
Grade:
biotech. grade
Bp:
127 °C (lit.)
Vapor pressure:
31 mmHg ( 37.7 °C)

$114.00


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grade

biotech. grade

Quality Segment

vapor pressure

31 mmHg ( 37.7 °C)

assay

99.5%

impurities

<0.050% water

color

APHA: <20

refractive index

n20/D 1.414 (lit.)

pH

12.3 (20 °C)

bp

127 °C (lit.)

mp

<−50 °C (lit.)

solubility

water: soluble 4.01 g/L at 20 °C

density

0.742 g/mL at 25 °C (lit.)

application(s)

peptide synthesis

SMILES string

CCN(C(C)C)C(C)C

InChI

1S/C8H19N/c1-6-9(7(2)3)8(4)5/h7-8H,6H2,1-5H3

InChI key

JGFZNNIVVJXRND-UHFFFAOYSA-N

General description

N, N-Diisopropylethylamine is a hindered non-nucleophilic amine base used in alkylation, aldol-like reactions, eliminations, and selective generation of enolates. It is widely used as a proton scavenger in organic synthesis. Due to its less nucleophilic nature, it produces less byproducts.
N, N-Diisopropylethylamine is a hindered non-nucleophilic amine base used in alkylation, aldol-like reactions, eliminations, and selective generation of enolates. It is widely used as a proton scavenger in organic synthesis. Due to its less nucleophilic nature, it produces less byproducts.
Our biotech solvents offer exceptional quality for reliable RNA extraction, ensuring optimal laboratory performance. With low water content and minimal residue, give clean UV spectra to minimize contamination.
  • High-Quality Biotech Solvents: Designed for optimal laboratory performance with low water content and minimal residues.
  • Ideal for RNA Extraction: Essential for genetic testing and research applications like PCR.
  • Ensures Integrity of Genetic Material: Promotes reliable and reproducible results.
  • Industry Compliant: Suitable for both academic and commercial laboratories, enhancing research efficiency.

Application

N,N-Diisopropylethylamine may be used in the synthesis of mannosylated ovalbumin peptides.
N, N-Diisopropylethylamine can be used as a base:
  • In the palladium (0)-catalyzed alkoxy carbonylation of allyl phosphates and acetate.
  • In the selective enolate formation along with boryl triflates.
  • In the C–N coupling of aryl halides with nitroarenes in the presence of nickel catalyst.


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387649900690D125806
description

99.5%, biotech. grade

description

purified by redistillation, 99.5%

description

purified by redistillation, ZerO2®, 99.5%

description

ReagentPlus®, ≥99%

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

grade

biotech. grade

grade

-

grade

-

grade

-

application(s)

peptide synthesis

application(s)

-

application(s)

-

application(s)

-

assay

99.5%

assay

99.5%

assay

99.5%

assay

≥99%

solubility

water: soluble 4.01 g/L at 20 °C

solubility

water: soluble 4.01 g/L at 20 °C

solubility

-

solubility

-

mp

<−50 °C (lit.)

mp

<−50 °C (lit.)

mp

<−50 °C (lit.)

mp

<−50 °C (lit.)


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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.1 °F

Flash Point (°C)

9.5 °C



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Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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