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49782

Sigma-Aldrich

Glycerol solution

puriss. p.a., 86-89% (T)

Synonym(s):
1,2,3-Propanetriol
Linear Formula:
HOCH2CH(OH)CH2OH · aq
CAS Number:
Molecular Weight:
92.09 (anhydrous basis)
Beilstein:
635685
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg

grade

puriss. p.a.

assay

86-89% (T)

form

viscous liquid

expl. lim.

2.6-11.3 %

impurities

≤0.001% aldehydes (as formaldehyde)
≤0.002% free acid (as CH3COOH)
≤0.05% fatty acid esters (as glycerol tributyrate)
11-14% water

ign. residue

≤0.01% (as SO4)

refractive index

n20/D 1.454

pH

5.5-8

bp

182 °C/20 mmHg (lit.)

density

1.252 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤2 mg/kg
sulfate (SO42-): ≤5 mg/kg

cation traces

Ca: ≤10 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤5 mg/kg
Mn: ≤1 mg/kg
NH4+: ≤5 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤1 mg/kg

SMILES string

OCC(O)CO

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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General description

Glycerol is widely used in industries based on food, polymer, resins, tobacco, detergents, explosives, drugs and personal care products. It is most commonly employed cheap feedstock in the chemical industry. Its transformation to various commercial value-added chemicals has been proposed. A fast enzymatic assay for the determination of glycerol based on its reaction with ATP has been described.

Application

Glycerol may be used in the synthesis of poly(glycerol sebacate) (PGS) pre-polymer, which is required for the fabrication of PGS scaffolds. It may be employed to protect the human red blood-cells from damage during the process of freezing and thawing.

Storage Class Code

10 - Combustible liquids

WGK Germany

WGK 3

Flash Point(F)

320.0 °F - closed cup

Flash Point(C)

160 °C - closed cup

Certificate of Analysis

Certificate of Origin

The mechanism of the protective action of glycerol against haemolysis by freezing and thawing.
J E LOVELOCK
Biochimica et biophysica acta, 11(1), 28-36 (1953-05-01)
Nafiseh Masoumi et al.
Journal of biomedical materials research. Part A, 101(1), 104-114 (2012-07-25)
Microfabricated poly(glycerol sebacate) (PGS) scaffolds may be applicable to tissue engineering heart valve leaflets by virtue of their controllable microstructure, stiffness, and elasticity. In this study, PGS scaffolds were computationally designed and microfabricated by laser ablation to match the anisotropy...
A rapid enzymatic assay for glycerol.
Garland PB and Randle PJ.
Nature, 196, 987 - 988 (1962)
Mario Pagliaro et al.
Angewandte Chemie (International ed. in English), 46(24), 4434-4440 (2007-05-02)
Today, industrial plants that produce glycerol are closing down and others are opening that use glycerol as a raw material, owing to the large surplus of glycerol formed as a by-product during the production of biodiesel. Research efforts to find...
Benoît Ranchoux et al.
The American journal of pathology, 185(2), 356-371 (2014-12-17)
Pulmonary veno-occlusive disease (PVOD) is an uncommon form of pulmonary hypertension (PH) characterized by progressive obstruction of small pulmonary veins and a dismal prognosis. Limited case series have reported a possible association between different chemotherapeutic agents and PVOD. We evaluated...

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