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MilliporeSigma

537616

Diethylene glycol monoethyl ether

ReagentPlus®, 99%

Synonym(s):

2-(2-Ethoxyethoxy)ethanol, CARBITOL, Diethylene glycol ethyl ether, Ethyldiglycol

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About This Item

Linear Formula:
C2H5OCH2CH2OCH2CH2OH
CAS Number:
Molecular Weight:
134.17
Beilstein/REAXYS Number:
1736441
EC Number:
MDL number:
UNSPSC Code:
12352112
PubChem Substance ID:
NACRES:
NA.21
Assay:
99%
Bp:
202 °C (lit.)
Vapor pressure:
0.12 mmHg ( 20 °C)

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vapor density

4.63 (vs air)

vapor pressure

0.12 mmHg ( 20 °C)

product line

ReagentPlus®

assay

99%

form

liquid

expl. lim.

1.2 %, 135 °F
23.5 %, 182 °F

dilution

(for general lab use)

refractive index

n20/D 1.427 (lit.)

bp

202 °C (lit.)

mp

-80 °C

solubility

water: soluble

density

0.999 g/mL at 25 °C (lit.)

SMILES string

CCOCCOCCO

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

Inchi Key

XXJWXESWEXIICW-UHFFFAOYSA-N

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1 of 4

This Item
11933018.03127W509043
assay

99%

assay

-

assay

≥98% (GC)

assay

≥99%

Quality Level

100

Quality Level

-

Quality Level

200

Quality Level

400

solubility

water: soluble

solubility

-

solubility

-

solubility

-

form

liquid

form

-

form

liquid

form

liquid

vapor pressure

0.12 mmHg ( 20 °C)

vapor pressure

0.12 mmHg ( 20 °C)

vapor pressure

0.13 hPa ( 20 °C)

vapor pressure

0.12 mmHg ( 20 °C)

density

0.999 g/mL at 25 °C (lit.)

density

0.999 g/mL at 25 °C (lit.)

density

0.99 g/cm3 at 20 °C

density

0.999 g/mL at 25 °C (lit.)

General description

Diethylene glycol monoethyl ether (DEGMEE) is an organic solvent commonly used in the cosmetic industry.[1] Its toxicity has been assessed.[2] Various thermodynamic and optical parameters of an aqueous solution of DEGMEE have been determined.[3] Its quantification along with diethylene glycol (DEG) and coumarin in food samples by gas chromatography-flame ionization technique has been reported.[4]

Application


  • A cautionary note on the effects of laboratory air contaminants on ambient ionization mass spectrometry measurements.: Highlights the influence of diethylene glycol monoethyl ether as a common laboratory contaminant that can affect the accuracy of mass spectrometry analyses, underscoring the importance of controlling environmental variables in high-precision analytical settings (Kumbhani SR et al., 2017).

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
CARBITOL is a trademark of The Dow Chemical Company or an affiliated company of Dow

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup


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Thermodynamic and optical studies of some ethylene glycol ethers in aqueous solutions at T = 298.15 K.
Dhondge SS, et al.
The Journal of Chemical Thermodynamics, 41(5), 577-585 (2009)
Simultaneous determination of diethylene glycol, diethylene glycol monoethyl ether, coumarin and caffeine in food items by gas chromatography.
Rahim AA, et al.
Food Chemistry, 126(3), 1412-1416 (2011)
Reproductive toxicology. Diethylene glycol monoethyl ether.
Environmental health perspectives, 105 Suppl 1, 209-210 (1997-02-01)
Roberta Censi et al.
Drug development and industrial pharmacy, 38(9), 1128-1133 (2011-12-23)
A microemulsion for the cutaneous release of quercetin was prepared. An aqueous phase, containing 40% Transcutol® P as solubilizing agent and permeation enhancer, was emulsified with Labrafil® as oil phase and Labrasol®/Capryol™ 90 as Solvent/Co-solvent. Quercetin was dissolved in the
Jeoung Hee Yoo et al.
Archives of pharmacal research, 33(3), 417-426 (2010-04-03)
Self-nanoemulsifying drug delivery system (SNEDDS) containing oil (Phosal 53 MCT), surfactant (Labrasol), and cosurfactant (Transcutol-HP or Lutrol-E400) was prepared to enhance solubility and dissolution of lutein. Ternary phase diagram of the SNEDDS was constructed to identify the self-emulsifying regions following

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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