72061

Sigma-Aldrich

Sodium triphosphate pentabasic

purum p.a., ≥98.0% (T)

Synonym(s):
Sodium tripolyphosphate pentabasic, Pentasodium tripolyphosphate
Linear Formula:
Na5P3O10
CAS Number:
Molecular Weight:
367.86
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21
Pricing and availability is not currently available.

grade

purum p.a.

assay

≥98.0% (T)
57-59% (calc. based on P2O5)

form

powder

pH

9.0-10.0 (25 °C, 1% in H2O)

solubility

water: soluble 148 g/L at 20 °C

anion traces

chloride (Cl-): ≤1000 mg/kg
sulfate (SO42-): ≤250 mg/kg

cation traces

Ca: ≤200 mg/kg
Cd: ≤50 mg/kg
Co: ≤50 mg/kg
Cu: ≤50 mg/kg
Fe: ≤50 mg/kg
Ni: ≤50 mg/kg
Pb: ≤50 mg/kg
Zn: ≤50 mg/kg

SMILES string

Na+.Na+.Na+.Na+.Na+.O-P(O-)(=O)OP(O-)(=O)OP(O-)(O-)=O

InChI

1S/5Na.H5O10P3/c;;;;;1-11(2,3)9-13(7,8)10-12(4,5)6/h;;;;;(H,7,8)(H2,1,2,3)(H2,4,5,6)/q5*+1;/p-5

InChI key

HWGNBUXHKFFFIH-UHFFFAOYSA-I

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Application

for the determination of BSB acc. to DIN 38409-H 51

Other Notes

Straight chain phosphates

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Meenakshi Malhotra et al.
International journal of nanomedicine, 8, 2041-2052 (2013-06-01)
Recently, cell-penetrating peptides have been proposed to translocate antibodies, proteins, and other molecules in targeted drug delivery. The proposed study presents the synthesis and characterization of a peptide-based chitosan nanoparticle for small interfering RNA (siRNA) delivery, in-vitro. Specifically, the synthesis...
Yan Huang et al.
Biomacromolecules, 13(11), 3868-3876 (2012-10-12)
Self-assembled micro- and nanogels are frequently prepared by mixing tripolyphosphate (TPP) with dilute chitosan solutions. Upon its addition, the TPP ionically cross-links the chitosan molecules into gel-like colloids that range from tens of nanometers to micrometers in diameter. These particles...
Barbara Steigenberger et al.
Organic letters, 15(2), 366-369 (2013-01-05)
The synthesis of the triphosphates of 5-hydroxymethyl-, 5-formyl-, and 5-carboxycytidine and the incorporation of these building blocks into long DNA fragments using the polymerase chain reaction (PCR) are reported. In this way DNA fragments containing multiple hmC, fC, and caC...
Bo Xiao et al.
Biomaterials, 34(30), 7471-7482 (2013-07-04)
The application of RNA interference (RNAi) for inflammatory bowel disease (IBD) therapy has been limited by the lack of non-cytotoxic, efficient and targetable small interfering RNA (siRNA) carriers. TNF-α is the major pro-inflammatory cytokine mainly secreted by macrophages during IBD....
Seigo Nagata et al.
Chemical & pharmaceutical bulletin, 60(9), 1212-1215 (2012-09-15)
We have developed an improved solid-phase method for the synthesis of 5'-triphosphates (5'-TPs) of oligoribonucleotides. The method is based on the use of salicyl phosphorochloridite as the phosphitylating reagent and the improvement is characterized by the use of the highly...

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