Ammonium bicarbonate

ReagentPlus®, ≥99.0%

Ammonium hydrogen carbonate
Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
EC Number:
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PubChem Substance ID:

Quality Level

vapor density

2.7 (vs air)

vapor pressure

513 hPa ( 50 °C)
67.1 hPa ( 20 °C)

product line





powder or crystals


7-8.5 (25 °C, 79.1 g/L)

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InChI key


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General description

Ammonium bicarbonate is an inorganic salt commonly used in the food industry. It can be generated by the interaction of gaseous carbon dioxide and aqueous ammonia. The addition of ammonium bicarbonate to microbial fuel cells (MFCs) has been reported to improve its functioning by altering the porosity and pore distribution of catalyst layers. A recent study reports the use of bubble column evaporator (BCE) based analysis of its thermal degradation in aqueous solution.


Ammonium bicarbonate (AMBIC) was used in the following studies:
  • To derivatize histone proteins from human monocyte-derived macrophages (MDM) by propionylation.
  • Destaining of silver-stained proteins in polyacrylamide gel bands during the peptide mass profiling using a mass spectrometer.
  • Digestion of proteins isolated from Xenopus egg extracts in coomassie blue-stained gel bands during the analysis of microtubule-binding proteins.


25, 500 g in poly bottle
1 kg in poly bottle

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC


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WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Pawel Olszowy et al.
Proteome science, 13, 24-24 (2015-09-29)
Histones and their post-translational modifications impact cellular function by acting as key regulators in the maintenance and remodeling of chromatin, thus affecting transcription regulation either positively (activation) or negatively (repression). In this study we describe a comprehensive, bottom-up proteomics approach...
Yao-Fa Lin et al.
Neural regeneration research, 14(12), 2183-2191 (2019-08-10)
Wallerian degeneration and nerve regeneration after injury are complex processes involving many genes, proteins and cytokines. After different peripheral nerve injuries the regeneration rate can differ. Whether this is caused by differential expression of genes and proteins during Wallerian degeneration...
Burdock GA.
Encyclopedia of Food and Color Additives, 1, 131-131 (1997)
Using ammonium bicarbonate as pore former in activated carbon catalyst layer to enhance performance of air cathode microbial fuel cell.
Li D, et al.
Journal of Power Sources, 272, 909-914 (2014)
Vincent Gache et al.
Methods in molecular medicine, 137, 29-43 (2007-12-19)
Microtubule-binding proteins are conveniently divided into two large groups: MAPs (microtubule-associated proteins), which can stabilize, anchor, and/or nucleate microtubules, and motors, which use the energy of ATP hydrolysis for a variety of functions, including microtubule network organization and cargo transportation...
Overcome challenges in synthesis and disulfide bond formation with protocols for Fmoc solid-phase peptide synthesis of peptides with cysteine and methionine.
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