F1635

SAFC

Formaldehyde solution

contains 10-15% methanol as stabilizer, 37 wt. % in H2O

Synonym(s):
Formalin
Linear Formula:
HCHO
CAS Number:
Molecular Weight:
30.03
Beilstein/REAXYS Number:
1209228
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

vapor density

1.03 (vs air)

vapor pressure

52 mmHg ( 37 °C)

form

liquid

autoignition temp.

572 °F

contains

10-15% methanol as stabilizer

concentration

37 wt. % in H2O
37-38%

application(s)

tissue processing: suitable

impurities

≤0.03% free acid (as HCOOH)

color

APHA: ≤10

pH

2.8-4.0

bp

97 °C

mp

-15 °C

density

1.09 g/mL at 25 °C (lit.)

SMILES string

[H]C([H])=O

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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General description

This product is 37wt% solution of formaldehyde in water. It contains 10-15% methanol as stabilizer.

Application

Formaldehyde solution has been used to prepare formaldehyde fixation/permeabilization solution that is employed to fix tissue samples.

Packaging

4 L in glass bottle
25, 500 mL in glass bottle

Biochem/physiol Actions

Induces tumors in the nasal epithelium of rats, and is suspected to be a human carcinogen. Potent mutagen.

Signal Word

Danger

hazcat

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

Target Organs

Respiratory system

storage_class_code

3 - Flammable liquids

WGK Germany

WGK 3

Flash Point(F)

133.0 °F - closed cup

Flash Point(C)

56.11 °C - closed cup

Certificate of Analysis

Certificate of Origin

Omer Barkai et al.
Pain, 160(6), 1281-1296 (2019-04-02)
Endogenous inflammatory mediators contribute to the pathogenesis of pain by acting on nociceptors, specialized sensory neurons that detect noxious stimuli. Here, we describe a new factor mediating inflammatory pain. We show that platelet-derived growth factor (PDGF)-BB applied in vitro causes...
Christopher Bruhn et al.
Genomics, proteomics & bioinformatics, 12(6), 255-265 (2014-12-03)
Cell cycle progression is coordinated with metabolism, signaling and other complex cellular functions. The investigation of cellular processes in a cell cycle stage-dependent manner is often the subject of modern molecular and cell biological research. Cell cycle synchronization and immunostaining...
Cindy S Ma et al.
The Journal of experimental medicine, 205(7), 1551-1557 (2008-07-02)
Hyper-immunoglobulin E syndrome (HIES) is a primary immune deficiency characterized by abnormal and devastating susceptibility to a narrow spectrum of infections, most commonly Staphylococcus aureus and Candida albicans. Recent investigations have identified mutations in STAT3 in the majority of HIES...
G R Moore et al.
Neurology, 55(10), 1506-1510 (2000-11-30)
To determine the pathologic basis of areas not exhibiting signal of the short-T2 component of the T2 relaxation distribution in MS, as studied in formalin-fixed brain. A myelin-specific MRI signal would be of great importance in assessing demyelination in patients...
Richard Brad Jones et al.
PLoS pathogens, 10(8), e1004287-e1004287 (2014-08-15)
Resting memory CD4+ T-cells harboring latent HIV proviruses represent a critical barrier to viral eradication. Histone deacetylase inhibitors (HDACis), such as suberanilohydroxamic acid (SAHA), romidepsin, and panobinostat have been shown to induce HIV expression in these resting cells. Recently, it...

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