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S9763

Sigma-Aldrich

Sodium phosphate dibasic

ACS reagent, ≥99.0%

Synonym(s):
Sodium hydrogenphosphate, Disodium phosphate, Disodium hydrogen phosphate, sec-Sodium phosphate
Linear Formula:
Na2HPO4
CAS Number:
Molecular Weight:
141.96
EC Number:
MDL number:
eCl@ss:
38070211
PubChem Substance ID:
NACRES:
NA.21

Quality Level

grade

ACS reagent

assay

≥99.0%

form

powder

impurities

≤0.002% Chloride (Cl)
≤0.01% Insoluble matter

loss

≤0.2% loss on drying, 105°C

pH

8.7-9.3 (25 °C, 5% in solution)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

solubility

water: 5% at 25 °C, clear

anion traces

sulfate (SO42-): ≤0.005%

cation traces

Fe: ≤0.002%
heavy metals: ≤0.001% (by ICP-OES)

SMILES string

[Na+].[Na+].[H]OP([O-])([O-])=O

InChI

1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2

InChI key

BNIILDVGGAEEIG-UHFFFAOYSA-L

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General description

Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.

Application

Sodium phosphate dibasic has been used in:
  • the preparation of phosphate buffer saline solution for perfusion procedure
  • western blot
  • indirect enzyme linked immunosorbent assay

Packaging

1, 2.5 kg in poly bottle
5, 12 kg in poly drum
100, 500 g in poly bottle

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Premixed tricalcium silicate/sodium phosphate dibasic cements for root canal filling
Wu Meng, et al.
Materials Chemistry and Physics (2021)
Response of Rainbow Trout (Oncorhynchus mykiss) Growing from 50 to 200 g to Supplements of Dibasic Sodium Phosphate in a Semipurified Diet
Rodehutscord M
The Journal of Nutrition (1996)
Glomerular calcification induced by bolus injection with dibasic sodium phosphate solution in Sprague-Dawley rats
Tsuchiya N, et al.
Toxicologic Pathology, 408-412 (2004)
Karsten Krug et al.
Cell, 183(5), 1436-1456 (2020-11-20)
The integration of mass spectrometry-based proteomics with next-generation DNA and RNA sequencing profiles tumors more comprehensively. Here this "proteogenomics" approach was applied to 122 treatment-naive primary breast cancers accrued to preserve post-translational modifications, including protein phosphorylation and acetylation. Proteogenomics challenged
Michael A Gillette et al.
Cell, 182(1), 200-225 (2020-07-11)
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and 101 matched normal adjacent tissues (NATs) incorporating genomics, epigenomics, deep-scale proteomics, phosphoproteomics, and acetylproteomics. Multi-omics clustering revealed four

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