Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

01480

Sigma-Aldrich

Acetylthiocholine iodide

≥99.0% (AT)

Synonym(s):

(2-Mercaptoethyl)trimethylammonium iodide acetate

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CH3COSCH2CH2N(CH3)3I
CAS Number:
Molecular Weight:
289.18
Beilstein/REAXYS Number:
3916578
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.83

Quality Level

assay

≥99.0% (AT)

ign. residue

≤0.05%

mp

205-210 °C (lit.)
205-210 °C

solubility

H2O: 0.1 g/mL, clear, colorless

storage temp.

2-8°C

SMILES string

[I-].CC(=O)SCC[N+](C)(C)C

InChI

1S/C7H16NOS.HI/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

NTBLZMAMTZXLBP-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Application

Acetylthiocholine iodide has been used as a substrate to determine anticholinesterase activity.
Substrate for the colorimetric determination of acetylcholinesterase activity.

Substrates

Acetylcholinesterase substrate and nicotinic acetylcholine receptor agonist.

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Belgin Sever et al.
International journal of biological macromolecules, 163, 1970-1988 (2020-09-16)
Alzheimer's disease (AD) is a complex, predominant, and progressive form of dementia. The treatment of AD alters depending on the cognitive and behavioral symptoms. The utility of cholinergic replacement by acetylcholinesterase (AChE) inhibitors in AD treatment has been well-documented so
Niko S Radulović et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 80, 114-129 (2015-03-15)
Herein we report on the comprehensive chemical analysis of the essential oils obtained from above- and underground parts of a previously unreported chemotype of Achillea falcata L. (Asteraceae) and, for the first time, on the biological/toxicological profile of its dominant/newly
Wei Li et al.
Fitoterapia, 98, 117-123 (2014-07-30)
Three new 2-(2-phenylethyl)chromone derivatives (1-3), together with thirteen known ones (4-16), were isolated from the EtOAc extract of Chinese agarwood induced by artificial holing, originating from Aquilaria sinensis (Lour.) Gilg (Thymelaeaceae). The chemical structures of the new compounds were identified
Satish N Dighe et al.
ACS omega, 5(48), 30971-30979 (2020-12-17)
Cholinesterases (ChE) are well-known drug targets for the treatment of Alzheimer's disease (AD). In continuation of work to develop novel cholinesterase inhibitors, we utilized a structure-based scaffold repurposing approach and discovered six novel ChE inhibitors from our recently developed DNA
K Y Khaw et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 21(11), 1303-1309 (2014-08-31)
Garcinia mangostana is a well-known tropical plant found mostly in South East Asia. The present study investigated acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities of G. mangostana extract and its chemical constituents using Ellman's colorimetric method. Cholinesterase inhibitory-guided approach led

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service