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04076

Sigma-Aldrich

6-(p-Toluidino)-2-naphthalenesulfonyl chloride

suitable for fluorescence, ≥98.0% (HPLC)

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Synonym(s):
2,6-TNS-Cl, 6-(4-Methylanilino)naphthalene-2-sulfonylchloride, 6-[(4-methylphenyl)amino]-2-naphthalenesulfonylchloride
Empirical Formula (Hill Notation):
C17H14ClNO2S
CAS Number:
Molecular Weight:
331.82
Beilstein:
6521872
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Assay

≥98.0% (HPLC)

solubility

DMF: soluble
acetonitrile: soluble

fluorescence

λex 381 nm in methanol

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

Cc1ccc(Nc2ccc3cc(ccc3c2)S(Cl)(=O)=O)cc1

InChI

1S/C17H14ClNO2S/c1-12-2-6-15(7-3-12)19-16-8-4-14-11-17(22(18,20)21)9-5-13(14)10-16/h2-11,19H,1H3

InChI key

NONZPGMJWHNDKP-UHFFFAOYSA-N

Application

6-(p-Toluidino)-2-naphthalenesulfonyl chloride is a fluorescent, hydrophobic probe utilized for labeling peptides to monitor conformational changes of a molecular assembly by measuring alterations in fluorescence intensity .

Analysis Note

Emmax: none
do not dissolve in DMSO

Other Notes

Probe for determining the polarity in biological matrices

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J.R. Lakowicz
Principles of Fluorescence Spectroscopy (1983)

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