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MilliporeSigma

07076

Sigma-Aldrich

Castor Oil, Hydrogenated,Ethoxylated

Synonym(s):

Cremophor® RH 40, Macrogolglycerol hydroxystearate, PEG-40 castor oil, Polyoxyl 40 hydrogenated castor oil, RH 40

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About This Item

CAS Number:
61788-85-0
MDL number:
MFCD01771439
UNSPSC Code:
12161900
NACRES:
NA.25

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impurities

≤0.2% sulfated ash (verfied on random samples only)
≤1 ppm ethylene oxide
≤10 ppm dioxan
≤10 ppm heavy metals (verfied on random samples only)
≤2 ppm arsenic (verfied on random samples only)
≤2.0% water
≤5000 ppm acetic acid
≤620 ppm diethylene glycol
≤620 ppm ethylene glycol

Quality Level

100

ign. residue

≤0.25% (verfied onrandom samples only)

acid value

≤0.8 mg KOH/g

hydroxyl value

60‑75 mg KOH/g

iodine value

≤1.0 g I2/100 g

saponification value

50‑60 mg KOH/g

suitability

suitable for acidity or alkalinity

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This Item
30906C5135388920
Sigma-Aldrich

Sigma-Aldrich

07076

Castor Oil, Hydrogenated,Ethoxylated

Castor Oil, Ethoxylated

Sigma-Aldrich

30906

Castor Oil, Ethoxylated

Castor Oil, Ethoxylated pH range 6.0-8.0

Sigma-Aldrich

C5135

Castor Oil, Ethoxylated

Sorbitan monopalmitate

Sigma-Aldrich

388920

Sorbitan monopalmitate

suitability

suitable for acidity or alkalinity

suitability

-

suitability

-

suitability

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

impurities

≤0.2% sulfated ash (verfied on random samples only), ≤10 ppm dioxan, ≤2 ppm arsenic (verfied on random samples only), ≤5000 ppm acetic acid, ≤620 ppm ethylene glycol, ≤1 ppm ethylene oxide, ≤2.0% water, ≤10 ppm heavy metals (verfied on random samples only), ≤620 ppm diethylene glycol

impurities

alkalinity, complies, ≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only), ≤0.1% oleic acid, ≤0.1% palmitic acid, ≤0.2% sulfated ash (verfied on random samples only), ≤0.20% ricinoleic acid, ≤0.5% water, ≤1 ppm ethylene oxide (verfied on random samples only), ≤1.0% free fatty acids, ≤10 ppm dioxan (verfied on random samples only), ≤10 ppm heavy metals (verfied on random samples only), ≤620 ppm diethylene glycol (verfied on random samples only), ≤620 ppm ethylene glycol (verfied on random samples only)

impurities

-

impurities

-

ign. residue

≤0.25% (verfied onrandom samples only)

ign. residue

≤0.2%

ign. residue

-

ign. residue

-

acid value

≤0.8 mg KOH/g

acid value

≤2.0 mg KOH/g

acid value

-

acid value

-

hydroxyl value

60‑75 mg KOH/g

hydroxyl value

65‑78 mg KOH/g

hydroxyl value

-

hydroxyl value

-

Application

Castor Oil, Hydrogenated,Ethoxylated is used to solubilize vitamins, water insoluble active substances and essential oils in water or mixtures of water and alcohol.

Analysis Note

congealing temperature 16-26°C

Other Notes

Castor Oil, Hydrogenated, Ethoxylated is the brand name for a range of non-ionic polyethoxylated detergents. It was developed for use as solubilizers and emulsifiers.

Legal Information

Cremophor is a registered trademark of BASF SE

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

467.6 °F

flash_point_c

242 °C

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6035
BCCM7386
BCCL5059
BCCL5058
BCCM3260

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Christofori M R R Nastiti et al.
Pharmaceutics, 12(2) (2020-02-06)
Resveratrol (RSV) is a potent lipophilic antioxidant with a low aqueous solubility. Novel nanoformulations have been successfully developed and evaluated to increase the potential of resveratrol as a skin targeting antioxidant. Nanoformulations were prepared using a spontaneous emulsification method, and
Allergic contact dermatitis to polyethylene glycol-7 hydrogenated castor oil.
M Kalavala et al.
Contact dermatitis, 56(5), 287-288 (2007-04-20)
William J Gradishar et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 23(31), 7794-7803 (2005-09-21)
ABI-007, the first biologically interactive albumin-bound paclitaxel in a nanameter particle, free of solvents, was compared with polyethylated castor oil-based standard paclitaxel in patients with metastatic breast cancer (MBC). This phase III study was performed to confirm preclinical studies demonstrating
Yun-Seok Rhee et al.
Archives of pharmacal research, 30(1), 114-123 (2007-03-03)
The aim of this study was to develop an aqueous parenteral formulation containing itraconazole (ITZ) using an o/w microemulsion system. A mixture of benzyl alcohol and medium chain triglyceride (3/1) was chosen as the oil phase. Pseudoternary phase diagrams of
Yukako Ito et al.
Journal of drug targeting, 13(6), 383-390 (2005-11-10)
Interferon alpha (IFN-alpha), patch preparations composed of three layers, water-insoluble backing layer, drug containing layer with absorption enhancer and surface layer containing pH-dependent polymer were prepared. As absorption enhancer, three surfactants, Gelucire44/14 (Lauroyl macrogol-32 glycerides), Labrasol (Caprylocaproyl macrogol-8 glycerides) and
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