113R-2

CD13 (EP117) Rabbit Monoclonal Primary Antibody

• Synonym(s): Aminopeptidase-N

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP117, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (113R-24); vial of 0.1 mL concentrate Research Use Only (113R-24-RUO); vial of 0.5 mL concentrate (113R-25); vial of 1.0 mL concentrate (113R-26); vial of 1.0 mL concentrate Research Use Only (113R-26-RUO); vial of 1.0 mL pre-dilute Research Use Only (113R-27-RUO); vial of 1.0 mL pre-dilute ready-to-use (113R-27); vial of 7.0 mL pre-dilute ready-to-use (113R-28); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (113R-28-RUO)
• manufacturer/tradename: Cell Marque^™
• concentration: 0.1-5 μg/mL (predilute); 2.5-125 μg/mL (concentrate)
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• isotype: IgG
• control: liver
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic, membranous
• Gene Information: human ... ANPEP(290)

Description

General description

CD13 (aminopeptidase-N) is a transmembrane protease present in many tissues and cell types (e.g., endothelial and epithelial cells, fibroblasts, and leukocytes). CD13 is expressed in various solid and hematological malignancies in humans and is useful in identifying acute myeloid leukemia when used in a panel including antibodies against CD13(+), CD34(+), CD117(+), CD16(-), and CD33(+). This protein is also expressed in myeloid sarcoma and anti-CD13 is useful in its identification using a panel.

In addition, it has been reported that CD13 is expressed in both normal and neoplastic liver tissue, where it exhibits a canalicular distribution pattern similar to that seen for polyclonal CEA and CD10. Thus, anti-CD13 can be useful as an additional marker in differentiating between HCC and non-hepatocellular neoplasms.

Quality

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Linkage

CD13 Positive Control Slides, Product No. 113S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

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Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable