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MilliporeSigma

137257

MES sodium salt

EMPROVE® EVOLVE

Synonym(s):

MES, Sodium Salt, 2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt

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About This Item

Empirical Formula (Hill Notation):
C6H12NNaO4S
CAS Number:
Molecular Weight:
217.22
UNSPSC Code:
12161700
Beilstein/REAXYS Number:
3765682
MDL number:

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Product Name

MES sodium salt, EMPROVE® EVOLVE

pH

5.5-6.7

InChI key

IRHWMYKYLWNHTL-UHFFFAOYSA-M

SMILES string

[Na+].[O-]S(=O)(=O)CCN1CCOCC1

InChI

1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1

biological source

synthetic

product line

EMPROVE® EVOLVE

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin and microbial, tested

useful pH range

5.5-6.7

pKa 

6.1
6.1

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

storage temp.

2-30°C

Quality Level

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This Item
M3058M5057PHG0008
biological source

synthetic

biological source

-

biological source

-

biological source

synthetic

suitability

suitable for manufacturing use

suitability

suitable for component for culture media, suitable for molecular biology

suitability

-

suitability

suitable for manufacturing use

form

powder

form

crystalline powder

form

crystalline

form

powder

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

pH

5.5-6.7

pH

-

pH

8.9-10.1 (1% in water)

pH

-

impurities

Endotoxin and microbial, tested

impurities

endotoxin and total aerobic microbial count, tested

impurities

-

impurities

Endotoxin and microbial; tested

Application

MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.MES Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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