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MilliporeSigma

137272

SAFC

Guanidine hydrochloride

EMPROVE® EVOLVE

Synonym(s):

Guanidine hydrochloride, Aminoformamidine hydrochloride, Aminomethanamidine hydrochloride, Guanidinium chloride

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About This Item

Linear Formula:
NH2C(=NH)NH2 · HCl
CAS Number:
Molecular Weight:
95.53
Beilstein/REAXYS Number:
3591990
MDL number:
UNSPSC Code:
12352107

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biological source

synthetic

Quality Level

product line

EMPROVE® EVOLVE

form

powder

impurities

Endotoxin, microbial, and trace metals; tested

pH

(25 °C, 4.6 - 6/573 g/L)

mp

180-185 °C (lit.)
180-185 °C (lit.)

solubility

water: 6 M at 20 °C, clear, colorless

density

1.3 g/cm3 (lit.)
1.3 g/cm3 (lit.)

suitability

suitable for manufacturing use

storage temp.

2-30°C

SMILES string

Cl[H].NC(N)=N

InChI

1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H

InChI key

PJJJBBJSCAKJQF-UHFFFAOYSA-N

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This Item
50933PHG0006G3272
form

powder

form

powder or crystals

form

powder

form

crystalline powder

solubility

water: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M at 20 °C, clear, colorless

solubility

H2O: 6 M, clear, colorless

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

density

1.3 g/cm3 (lit.)

product line

EMPROVE® EVOLVE

product line

BioUltra

product line

-

product line

-

biological source

synthetic

biological source

synthetic

biological source

synthetic

biological source

synthetic (organic)

impurities

Endotoxin, microbial, and trace metals; tested

impurities

DNases, none detected, RNases, none detected, insoluble matter, passes filter test, phosphatases, none detected, proteases, none detected

impurities

Endotoxin, microbial, and trace metals; tested

impurities

≤0.3% water (Karl Fischer)

General description

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Application

Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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