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17797

Sigma-Aldrich

Physcion

≥98.0% (TLC)

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Synonym(s):
1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, 6-O-Methylemodin, 6-Methoxychrysophanic acid, Emodin-3-methyl ether, Parietin, Rheochrysidin
Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
Molecular Weight:
284.26
Beilstein:
6770499
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

Assay

≥98.0% (TLC)

antibiotic activity spectrum

fungi

SMILES string

COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1

InChI

1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3

InChI key

FFWOKTFYGVYKIR-UHFFFAOYSA-N

Gene Information

human ... ELA2(1991)

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This Item
M5255PHL8975793893
Physcion ≥98.0% (TLC)

Sigma-Aldrich

17797

Physcion

Mycophenolic acid ≥98%

Sigma-Aldrich

M5255

Mycophenolic acid

Physcion phyproof® Reference Substance

PHL89757

Physcion

Physcion analytical standard

Supelco

93893

Physcion

antibiotic activity spectrum

fungi

antibiotic activity spectrum

-

antibiotic activity spectrum

-

antibiotic activity spectrum

-

Quality Level

100

Quality Level

300

Quality Level

-

Quality Level

100

Gene Information

human ... ELA2(1991)

Gene Information

human ... IMPDH1(3614), IMPDH2(3615)

Gene Information

-

Gene Information

-

Application

Physcion can be used to study antibiotics, antifungals, bioactive small molecules and cell biology. Physcion has been used in a study to test the cytotoxicity of juglanthraquinone C on human cancer cells. Physcion has also been used in a study that investigated the metabolic regulatory effects of Rheum undulatum in a high-fat diet model.

Biochem/physiol Actions

Anthraquinone-derivative found in medicinal herbs.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Jie Tian et al.
Journal of separation science, 35(1), 145-152 (2011-12-07)
In this paper, two methods based on organic solvent dispersive liquid-liquid microextraction (OS-DLLME) and ionic liquid dispersive liquid-liquid microextraction (IL-DLLME) coupled with high-performance liquid chromatography have been critically compared for analyzing emodin and its metabolites (aloe-emodin, anthraquinone-2-carboxylic acid, rhein, danthron
Yao Yao et al.
Apoptosis : an international journal on programmed cell death, 17(8), 832-841 (2012-04-10)
Juglanthraquinone C (1,5-dihydroxy-9,10-anthraquinone-3-carboxylic acid, JC), a naturally occurring anthraquinone isolated from the stem bark of Juglans mandshurica, shows strong cytotoxicity in various human cancer cells in vitro. Here, we first performed a structure-activity relationship study of six anthraquinone compounds (JC
Santosh Pandit et al.
Biofouling, 28(3), 279-287 (2012-03-23)
Polygonum cuspidatum is a plant with spreading rhizomes and numerous reddish-brown stems that has been used in Korean folk medicine to improve oral hygiene. Nevertheless, there are no reports related to its possible effect on the virulence of dental biofilms.
M Bačkorová et al.
Toxicology in vitro : an international journal published in association with BIBRA, 25(1), 37-44 (2010-09-15)
One of the ways for searching for potentially new anti-cancer drugs is the testing of various naturally synthesized compounds. Lichens are a source of unique chemical agents of which some have already been proved to be effective against various cancer
Ming-Yi Shen et al.
PloS one, 6(11), e27480-e27480 (2011-11-17)
Plants provide a rich source of lead compounds for a variety of diseases. A novel approach combining phytochemistry and chemotaxis assays was developed and used to identify and study the mechanisms of action of the active compounds in F. japonica

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