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Sigma-Aldrich

9-Oxo-10(9H)-acridineacetic acid

for HPLC derivatization, ≥99.0% (T)

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Synonym(s):
(9,10-Dihydro-9-oxo-10-acridinyl)acetic acid, 10-(Carboxymethyl)-9(10H)acridone
Empirical Formula (Hill Notation):
C15H11NO3
CAS Number:
Molecular Weight:
253.25
Beilstein:
227508
MDL number:
PubChem Substance ID:
NACRES:
NA.32

grade

for HPLC derivatization

Quality Level

Assay

≥99.0% (T)

form

solid

mp

~289 °C (dec.)

SMILES string

OC(=O)CN1c2ccccc2C(=O)c3ccccc13

InChI

1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)

InChI key

UOMKBIIXHQIERR-UHFFFAOYSA-N

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This Item
150215775525E0656
9(10H)-Acridanone 99%

Sigma-Aldrich

150215

9(10H)-Acridanone

ER-27319 ≥98% (HPLC), solid

Sigma-Aldrich

E0656

ER-27319

form

solid

form

solid

form

solid

form

solid

mp

~289 °C (dec.)

mp

>300 °C (lit.)

mp

144-149 °C

mp

-

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

grade

for HPLC derivatization

grade

-

grade

-

grade

-

Application

9-Oxo-10(9H)-acridineacetic acid and its analogs are used to study their potential activity as interferon inducers.

Other Notes

Reagent for pre-column derivatization of amino acids for fluorescent determination in HPLC; Building block in pharmaceutics

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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A detailed analysis of the literature data gives contradictory information about the role of interferon-alpha in the regulation of apoptosis, while there are almost no data on the participation of cycloferon in this process. Results of original experiments in recent
Competition of sodium salt of 9-oxo-10-acridineacetic acid with analogs during induction of interferon in the mouse bone marrow-derived macrophages.
Szulc B, Inglot AD, Szulc Z, Mlochowski J.
Arch. Immunol. Ther. Exp., 33, 287-297 (1985)
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