17928

Sigma-Aldrich

O-Methyl-O′-succinylpolyethylene glycol 2′000

Synonym(s):
O-(Succinyl)-O′-methylpolyethylene glycol 2′000, Polyethylene glycol 2′000 monomethyl ether succinate
Linear Formula:
CH3O(CH2CH2O)nCOCH2CH2COOH
CAS Number:
MDL number:
NACRES:
NA.26
Pricing and availability is not currently available.

Quality Level

mol wt

Mr ~2100

mp

50-53 °C

Ω-end

carboxylic acid

α-end

methoxy

storage temp.

−20°C

Application

Polyethylene glycol 2000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.

Packaging

5 g in poly bottle

Biochem/physiol Actions

O-Methyl-O′-succinylpolyethylene glycol 2′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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