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18726

Nα-Methyl-L-ornithine monohydrochloride

≥98% (TLC), powder

Synonym(s):

(S)-5-Amino-2-(methylamino)pentanoic acid hydrochloride, N-Me-Orn-OH · HCl

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10 MG

$35.40

100 MG

$204.00

$35.40


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About This Item

Empirical Formula (Hill Notation):
C6H14N2O2 · HCl
CAS Number:
Molecular Weight:
182.65
Beilstein/REAXYS Number:
6117952
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.32

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Product Name

Nα-Methyl-L-ornithine monohydrochloride, ≥98% (TLC)

Quality Level

assay

≥98% (TLC)

form

powder

optical activity

[α]/D +27.0±1.0°, c = 1 in 1 M HCl

composition

carbon, 38.7-40.2%
nitrogen, 14.9-15.7%

SMILES string

Cl.CN[C@@H](CCCN)C(O)=O

InChI

1S/C6H14N2O2.ClH/c1-8-5(6(9)10)3-2-4-7;/h5,8H,2-4,7H2,1H3,(H,9,10);1H/t5-;/m0./s1

InChI key

OUPNMQRLBAANLP-JEDNCBNOSA-N

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This Item
3031219773A5131
assay

≥98% (TLC)

assay

≥98.0% (TLC)

assay

≥96% (TLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

200

form

powder

form

-

form

powder

form

powder

optical activity

[α]/D +27.0±1.0°, c = 1 in 1 M HCl

optical activity

[α]/D 27.5±1.5°, c = 0.1 in 1 M HCl

optical activity

[α]/D +11.5±1.0°, c = 1 in H2O

optical activity

-

composition

carbon, 38.7-40.2%

composition

-

composition

-

composition

-

Biochem/physiol Actions

Nα-Methyl-L-ornithine has been identified as an inhibitor of nitric oxidase synthase in macrophages. [1]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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T B McCall et al.
British journal of pharmacology, 102(1), 234-238 (1991-01-01)
1. The synthesis of nitric oxide (NO) from L-arginine by rat peritoneal neutrophils (PMN) and the murine macrophage cell-line J774 and the inhibition of this synthesis by N-iminoethyl-L-ornithine (L-NIO), NG-monomethyl-L-arginine (L-NMMA), NG-nitro-L-arginine (L-NNA) and its methyl ester (L-NAME) were investigated.
D J Gordon et al.
Biochemistry, 40(28), 8237-8245 (2001-07-11)
A potential goal in the prevention or therapy of Alzheimer's disease is to decrease or eliminate neuritic plaques composed of fibrillar beta-amyloid (Abeta). In this paper we describe N-methyl amino acid containing congeners of the hydrophobic "core domain" of Abeta

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