22630

Sigma-Aldrich

Quinine hydrochloride dihydrate

BioReagent, suitable for fluorescence, ≥98.0% (NT)

Synonym(s):
(8α, 9R)-6′-Methoxycinchonan-9-ol monohydrochloride dihydrate
Empirical Formula (Hill Notation):
C20H24N2O2 · HCl · 2H2O
CAS Number:
Molecular Weight:
396.91
Beilstein/REAXYS Number:
6112655
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.32

Quality Level

product line

BioReagent

assay

≥98.0% (NT)

optical activity

[α]20/D −230±5°, c = 2% in 0.1 M HCl

impurities

≤10% dihydroquinine hydrochloride (HPLC)

solubility

H2O: soluble

fluorescence

λex 322 nm; λem 450 nm in H2O
λex 347 nm; λem 448 nm in 0.5 M sulfuric acid

suitability

suitable for fluorescence

SMILES string

O.O.Cl.COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2.ClH.2H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;2*1H2/t13-,14-,19-,20+;;;/m0.../s1

InChI key

MPQKYZPYCSTMEI-FLZPLBAKSA-N

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Pictograms

Exclamation markHealth hazard

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Aptamer-ligand recognition studied by native ion mobility-mass spectrometry.
Daems, et al.
Talanta, 224, 121917-121917 (2020)
Carl Esben Poulsen et al.
Analytical chemistry, 87(12), 6265-6270 (2015-05-20)
The determination of pharmacokinetic properties of drugs, such as the distribution coefficient (D) is a crucial measurement in pharmaceutical research. Surprisingly, the conventional (gold standard) technique used for D measurements, the shake-flask method, is antiquated and unsuitable for the testing...
Jaekyun Choi et al.
eNeuro, 7(2) (2020-03-30)
Feeding, a critical behavior for survival, consists of a complex series of behavioral steps. In Drosophila larvae, the initial steps of feeding are food choice, during which the quality of a potential food source is judged, and ingestion, during which...
Colin Harvey-Lewis et al.
Psychopharmacology, 231(13), 2633-2645 (2014-02-19)
Opioid-dependent humans are reported to show accelerated delay discounting of opioid rewards when compared to monetary rewards. It has been suggested that this may reflect a difference in discounting of consumable and non-consumable goods not specific to dependent individuals. Here...
Yu-Chieh David Chen et al.
Cell reports, 29(4), 961-973 (2019-10-24)
Taste drives appropriate food preference and intake. In Drosophila, taste neurons are housed in both external and internal organs, but the latter have been relatively underexplored. Here, we report that Poxn mutants with a minimal taste system of pharyngeal neurons...

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