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MilliporeSigma

231M-1

Calponin (CALP) Mouse Monoclonal Antibody

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1 ML

$129.00

0.1 ML

$181.00

7 ML

$402.00

0.5 ML

$449.00

1 ML

$655.00

$129.00


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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

CALP, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (231M-14)
vial of 0.5 mL concentrate (231M-15)
bottle of 1.0 mL predilute (231M-17)
vial of 1.0 mL concentrate (231M-16)
bottle of 7.0 mL predilute (231M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

appendix

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Quality Level

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This Item
231R-1230R-1451M-1
biological source

mouse

biological source

rabbit

biological source

rabbit

biological source

mouse

clone

CALP, monoclonal

clone

EP798Y, monoclonal

clone

E89, monoclonal

clone

hHCD, monoclonal

species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

diluted ascites fluid

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Analysis Note


IVD

IVD

IVD

RUO

General description

Calponin is a 34 kD polypeptide that interacts with actin, tropomyosin, and calmodulin. It is involved in smooth muscle contraction mechanism and is restricted exclusively to smooth muscle tissue. Anti-calponin has been found to be useful in differentiating benign sclerosing lesions of the breast from carcinoma. Calponin positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma.

Other Notes

Calponin Positive Control Slides, Product No. 231S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: [email protected]

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Antibodies to novel myoepithelium-associated proteins distinguish be-nign lesions and carcinoma in situ from invasive carcinoma of the breast
Wang NP, Wan BC, et al.
Appl. Immunohistochem., 5(3), 141-151 (1997)
T Nagao et al.
Cancer, 83(7), 1292-1299 (1998-10-08)
Malignant myoepithelioma (MME) of the salivary gland, also known as myoepithelial carcinoma, is rare and its biologic behavior has not been clarified fully. Ten cases of MME were analyzed for their clinicopathologic features and immunohistochemical characteristics, focusing on prognostic factors
Jason L Hornick et al.
The American journal of surgical pathology, 27(9), 1183-1196 (2003-09-10)
Myoepitheliomas and mixed tumors were only recently recognized to occur primarily in soft tissue, and only small case numbers have been described. To characterize these tumors further and to evaluate prognostic parameters, 101 myoepithelial tumors of soft tissue were retrieved
J C Fanburg-Smith et al.
Human pathology, 30(11), 1336-1343 (1999-11-26)
Angiomatoid "malignant" fibrous histiocytoma (AMFH) has been considered to be a low-grade sarcoma of childhood, and, with its fibrous pseudocapsule, angiomatoid change, dense lymphoplasmacytic response, and proliferation of spindled or round cells, has been classified as a fibrohistiocytic neoplasm. We
A T Savera et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(11), 1093-1100 (1997-12-05)
Myoepithelial cells of salivary glands have a complex cytoskeletal immunophenotype. To elaborate the smooth muscle phenotype of salivary gland myoepithelium and to assess its contribution to the histogenesis of pleomorphic adenomas, we evaluated the immunohistochemical expression of three novel monoclonal

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