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231M-1

Sigma-Aldrich

Calponin (CALP) Mouse Monoclonal Antibody

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NACRES:
NA.41

biological source

mouse

Quality Level

100
500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

CALP, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (231M-14)
vial of 0.5 mL concentrate (231M-15)
bottle of 1.0 mL predilute (231M-17)
vial of 1.0 mL concentrate (231M-16)
bottle of 7.0 mL predilute (231M-18)

manufacturer/tradename

Cell Marque™

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

appendix

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

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This Item
230R-1MABT1504ABT129
Calponin (CALP) Mouse Monoclonal Antibody

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231M-1

Calponin (CALP) Mouse Monoclonal Antibody

Caldesmon (E89) Rabbit Monoclonal Primary Antibody

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230R-1

Caldesmon (E89) Rabbit Monoclonal Primary Antibody

Anti-Calponin Antibody, clone CALP from mouse, clone N3/16, clone CALP

Sigma-Aldrich

MABT1504

Anti-Calponin Antibody, clone CALP

Anti-Calponin-1 Antibody from rabbit, purified by affinity chromatography

Sigma-Aldrich

ABT129

Anti-Calponin-1 Antibody

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

-

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

clone

CALP, monoclonal

clone

E89, monoclonal

clone

CALP, monoclonal, N3/16, monoclonal

clone

polyclonal

form

buffered aqueous solution

form

buffered aqueous solution

form

-

form

-

species reactivity

human

species reactivity

human

species reactivity

human, bovine, porcine

species reactivity

human

General description

Calponin is a 34 kD polypeptide that interacts with actin, tropomyosin, and calmodulin. It is involved in smooth muscle contraction mechanism and is restricted exclusively to smooth muscle tissue. Anti-calponin has been found to be useful in differentiating benign sclerosing lesions of the breast from carcinoma. Calponin positivity has also been noted in malignant myoepithelioma and pleomorphic adenoma of salivary gland origin, as well as angiomatoid malignant fibrous histiocytoma.

Quality


IVD
IVD
IVD
RUO

Linkage

Calponin Positive Control Slides, Product No. 231S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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T1503
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25G
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705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

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Antibodies to novel myoepithelium-associated proteins distinguish be-nign lesions and carcinoma in situ from invasive carcinoma of the breast
Wang NP, Wan BC, et al.
Appl. Immunohistochem., 5(3), 141-151 (1997)
T Nagao et al.
Cancer, 83(7), 1292-1299 (1998-10-08)
Malignant myoepithelioma (MME) of the salivary gland, also known as myoepithelial carcinoma, is rare and its biologic behavior has not been clarified fully. Ten cases of MME were analyzed for their clinicopathologic features and immunohistochemical characteristics, focusing on prognostic factors
Jason L Hornick et al.
The American journal of surgical pathology, 27(9), 1183-1196 (2003-09-10)
Myoepitheliomas and mixed tumors were only recently recognized to occur primarily in soft tissue, and only small case numbers have been described. To characterize these tumors further and to evaluate prognostic parameters, 101 myoepithelial tumors of soft tissue were retrieved
A T Savera et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 10(11), 1093-1100 (1997-12-05)
Myoepithelial cells of salivary glands have a complex cytoskeletal immunophenotype. To elaborate the smooth muscle phenotype of salivary gland myoepithelium and to assess its contribution to the histogenesis of pleomorphic adenomas, we evaluated the immunohistochemical expression of three novel monoclonal
J C Fanburg-Smith et al.
Human pathology, 30(11), 1336-1343 (1999-11-26)
Angiomatoid "malignant" fibrous histiocytoma (AMFH) has been considered to be a low-grade sarcoma of childhood, and, with its fibrous pseudocapsule, angiomatoid change, dense lymphoplasmacytic response, and proliferation of spindled or round cells, has been classified as a fibrohistiocytic neoplasm. We

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