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MilliporeSigma

239M-1

Collagen Type IV (CIV22) Mouse Monoclonal Antibody

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$129.00

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$181.00

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$421.00

7 ML

$423.00

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$643.00

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
CIV22, monoclonal
Application:
IHC (p)
Citations:
10

Key Documents

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biological source

mouse

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

CIV22, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (239M-14), vial of 0.5 mL concentrate (239M-15), bottle of 1.0 mL predilute (239M-17), vial of 1.0 mL concentrate (239M-16), bottle of 7.0 mL predilute (239M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG1

control

lung

shipped in

wet ice

storage temp.

2-8°C

Quality Level

100, 500

Gene Information

human ... COL4A1(1282)

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1 of 4

This Item
AB756PSAB4200709C1926
Collagen Type IV (CIV22) Mouse Monoclonal Antibody

Sigma-Aldrich

239M-1

Collagen Type IV (CIV22) Mouse Monoclonal Antibody

Anti-Collagen Antibody, Type IV Chemicon®, from rabbit

Sigma-Aldrich

AB756P

Anti-Collagen Antibody, Type IV

Anti-Collagen Type IV antibody, Mouse monoclonal clone col-94, purified from hybridoma cell culture

Sigma-Aldrich

SAB4200709

Anti-Collagen Type IV antibody, Mouse monoclonal

Monoclonal Anti-Collagen, Type IV antibody produced in mouse clone COL-94, ascites fluid

Sigma-Aldrich

C1926

Monoclonal Anti-Collagen, Type IV antibody produced in mouse

conjugate

unconjugated

conjugate

-

conjugate

-

conjugate

unconjugated

clone

CIV22, monoclonal

clone

polyclonal

clone

col-94, monoclonal

clone

COL-94, monoclonal

antibody form

culture supernatant

antibody form

purified antibody

antibody form

purified from hybridoma cell culture

antibody form

ascites fluid

biological source

mouse

biological source

rabbit

biological source

-

biological source

mouse

species reactivity

human

species reactivity

mouse

species reactivity

monkey, human

species reactivity

human

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

General description

Collagen Type IV is the major component of the basal lamina so antibodies to this molecule confirm its presence and reveal the morphological appearance of the structure. Normal tissue stains with this antibody in a fashion consistent with the sites of mesenchymal elements and epithelial basal laminae. Anti-Collagen IV can also be useful in the classification of soft tissue tumors: schwannomas and leiomyomas. Their well-differentiated, malignant counterparts usually immunoreact with this antibody. The vascular nature of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma can be revealed by this antibody with greater reliability than non-specific stains (e.g. silver reticulum)

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD
IVD
IVD
RUO

Other Notes

Collagen Type IV Positive Control Slides, Product No. 239S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

Lot/Batch Number
0000515352
0000515352
0000479300
0000479300
0000479309

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S Damiani et al.
Virchows Archiv : an international journal of pathology, 434(3), 227-234 (1999-04-06)
A retrospective study was made of 38 selected brest tumours with a poorly differentiated in situ duct component. These were classified on haematoxylin and eosin (H&E) as ductal carcinoma in situ (DCIS; 10 cases), DCIS with invasion (17 cases) and
S H Barsky et al.
The American journal of surgical pathology, 7(7), 667-677 (1983-10-01)
A new method has been developed for identifying blood vessel capillaries and distinguishing them from lymphatic capillaries. Highly purified antibodies to two ubiquitous components of basement membrane--Type IV collagen and laminin--were applied to fresh-frozen and formalin-fixed tissue sections rich in
J P McArdle et al.
International journal of cancer, 34(5), 633-638 (1984-11-15)
The basal lamina in a variety of metastatic tumours in brain was assessed with an antibody to type-IV collagen and the indirect immunoperoxidase technique. The antibody was raised in rabbits against type-IV collagen isolated from human placental tissue. Basal lamina
P De Iorio et al.
Anticancer research, 21(2B), 1395-1399 (2001-06-09)
The prognostic variability in breast cancer patients prompted the authors to investigate specific biological markers for the identification of high-risk breast cancer groups. In the present study, attention was focused on the interaction between tumor cells and the extracellular matrix
M Määttä et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 49(6), 711-726 (2001-05-25)
Laminins (Ln), together with Type IV collagen and nidogen-1, form the structural integrity of the basement membranes (BM). In this study we used immunohistochemistry to show the distribution of laminin chains alpha1, alpha3, alpha5, beta1, beta2, beta3, gamma1, gamma2, as
View All Related Papers

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