246R-1

E-cadherin (EP700Y) Rabbit Monoclonal Primary Antibody

• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP700Y, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (246R-14); vial of 0.5 mL concentrate (246R-15); bottle of 1.0 mL predilute (246R-17); vial of 1.0 mL concentrate (246R-16); bottle of 7.0 mL predilute (246R-18)
• manufacturer/tradename: Cell Marque^™
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200
• isotype: IgG
• control: breast
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: membranous

Description

General description

E-cadherin is a transmembrane protein that is involved in cell adhesion through the formationof adherens junctions between cells. It is expressed in cells of epithelial lineage. Anti-E-cadherin stains positively in the glandular epithelium as well as carcinomas of the gastrointestinaltract and breast. E-cadherin immunohistochemistry may also aid in the differentiation ofbreast ductal carcinomas (with membranous stain) from lobular carcinomas (with loss of themembranous stain).

Packaging

0.1, 0.5, 1, 7 mL

Quality

IVD

IVD

IVD

RUO

Linkage

E-cadherin Positive Control Slides, Product No. 246S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC