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283M-1

HBME-1 (HBME-1) Mouse Monoclonal Antibody

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Pack SizeSKUAvailabilityPrice
1 mL
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$149.00
0.1 mL
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$185.00
7 mL
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$403.00
0.5 mL
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$465.00
1 mL
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$702.00

About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
HBME-1, monoclonal
Application:
IHC (p)
Citations:
6

$149.00


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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

HBME-1, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (283M-14), vial of 0.5 mL concentrate (283M-15), bottle of 1.0 mL predilute (283M-17), vial of 1.0 mL concentrate (283M-16), bottle of 7.0 mL predilute (283M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgMκ

control

mesothelioma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic, membranous

General description

Hector Battifora mesothelial-1 (HBME-1) is a membrane antigen that exists in the microvilli ofmesothelial cells and other epithelial cells. Anti-HBME-1 labels thyroid papillary carcinomaand follicular carcinoma but not normal thyroid making it a valuable marker for distinguishingthyroid malignancies from benign thyroid lesions. It has also been demonstrated to labelmesothelial cells, both benign and malignant (malignant mesothelioma), and thus can aid inthe identification of mesothelioma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]
HBME-1 Positive Control Slides, Product No. 283S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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storage temp.

2-8°C

storage temp.

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storage temp.

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A C Bateman et al.
Histopathology, 30(1), 49-56 (1997-01-01)
Histological diagnosis of malignant mesothelioma and differentiation from adenocarcinoma is often difficult. Definitive pathological confirmation of malignant mesothelioma requires demonstration of an appropriate immunohistochemical phenotype. Selection of an optimum panel of immunohistochemical antibodies for the reliable identification of malignant mesothelioma
C C Cheung et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 14(4), 338-342 (2001-04-13)
In thyroid, the diagnosis of papillary carcinoma (PC) is based on nuclear features; however, identification of these features is inconsistent and controversial. Proposed markers of PC include HBME-1, specific cytokeratins (CK) such as CK19, and ret, the latter reflecting a
A Coli et al.
Journal of experimental & clinical cancer research : CR, 26(2), 221-227 (2007-08-30)
Ninety-six thyroid lesions were immunohistochemically evaluated for HBME-1 and Galectin-3 expression including nodules with cytological atypia, the latter defined as nuclear features suggestive but not diagnostic of papillary thyroid carcinoma. Thirty nodules with cytological atypia, 49 papillary thyroid carcinomas (PTCs)



Global Trade Item Number

SKUGTIN
283M-180841683133032
283M-170841683133025
283M-150841683133001
283M-140841683132998
283M-160841683133018

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