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30906

Sigma-Aldrich

Castor Oil, Ethoxylated

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Synonym(s):
Cremophor® ELP, Kolliphor® ELP, PEG-35 castor oil, Polyoxyl-35 castor oil
CAS Number:
MDL number:
NACRES:
NA.25

description

non-ionic

Quality Level

form

paste

impurities

alkalinity, complies
≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only)
≤0.1% oleic acid
≤0.1% palmitic acid
≤0.2% sulfated ash (verfied on random samples only)
≤0.20% ricinoleic acid
≤0.5% water
≤1 ppm ethylene oxide (verfied on random samples only)
≤1.0% free fatty acids
≤10 ppm dioxan (verfied on random samples only)
≤10 ppm heavy metals (verfied on random samples only)
≤620 ppm diethylene glycol (verfied on random samples only)
≤620 ppm ethylene glycol (verfied on random samples only)

ign. residue

≤0.2%

pH

5.0-7.0 (1 g/10 mL in H2O)

viscosity

600-750 mPa.s(25 °C)

acid value

≤2.0 mg KOH/g

hydroxyl value

65‑78 mg KOH/g

iodine value

25‑35 g/100g

saponification value

65‑70 mg KOH/g

cation traces

K: ≤15 ppm

InChI

1S/C4H7Cl2NO2/c5-1-3(2-6)9-4(7)8/h3H,1-2H2,(H2,7,8)

InChI key

JMNCUXPHXKHBPY-UHFFFAOYSA-N

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1 of 4

This Item
C5135PHR29721547200
vibrant-m

30906

Castor Oil, Ethoxylated

vibrant-m

C5135

Castor Oil, Ethoxylated

vibrant-m

PHR2972

Castor Oil

vibrant-m

1547200

Polyoxyl 35 castor oil

impurities

alkalinity, complies, ≤0.1% oleic acid, ≤0.2% sulfated ash (verfied on random samples only), ≤0.5% water, ≤1.0% free fatty acids, ≤10 ppm heavy metals (verfied on random samples only), ≤620 ppm ethylene glycol (verfied on random samples only), ≤ acetic acid (≤0.5 g/100g (%) verfied on random samples only), ≤0.20% ricinoleic acid, ≤10 ppm dioxan (verfied on random samples only), ≤0.1% palmitic acid, ≤620 ppm diethylene glycol (verfied on random samples only), ≤1 ppm ethylene oxide (verfied on random samples only)

impurities

-

impurities

-

impurities

-

description

non-ionic

description

non-ionic

description

-

description

-

Quality Level

100

Quality Level

200

Quality Level

100, 300

Quality Level

-

cation traces

K: ≤15 ppm

cation traces

-

cation traces

-

cation traces

-

viscosity

600-750 mPa.s(25 °C)

viscosity

-

viscosity

-

viscosity

-

Application

Kolliphor® is used to emulsify and solubilize oils and other water-insoluble substances. Similar to Kolliphor® EL but with lower water content and differences in viscosity.

Analysis Note

relative density D (25/25) 1.05-1.06

Legal Information

Cremophor is a registered trademark of BASF SE
Kolliphor is a registered trademark of BASF

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

494.6 °F - Not applicable

flash_point_c

257 °C - Not applicable


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The core-in-cup matrix tablets of Metoprolol succinate were prepared by wet granulation technique. Of all the investigated formulations, the optimized formulation of MS-09 followed zero-order kinetics of drug release. Trail on MS-09 was formulated using 7.5% hydrogenated castor-oil (HCO) and
Hideki Ichikawa et al.
Current drug delivery, 4(2), 131-140 (2007-04-26)
The effects of the formulation and particle composition of gadolinium (Gd)-containing lipid nanoemulsion (Gd-nanoLE) on the biodistribution of Gd after its intravenous (IV) injection in D(1)-179 melanoma-bearing hamsters were evaluated for its application in cancer neutron-capture therapy. Gd-nanoLEs whose particles
Enas A Mahmoud et al.
AAPS PharmSciTech, 10(1), 183-192 (2009-02-25)
The purpose of this study was to combine the advantages of self-nanoemulsifying drug delivery systems and tablets as a conventional dosage form emphasizing the excipients' effect on the development of a new dosage form. Systems composed of HCO-40, Transcutol HP
Siva Narayanan et al.
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This study compared clinical outcomes and nursing labor costs associated with (a) balsam Peru, hydrogenated castor oil, and trypsin (BCT) ointment; (b) BCT + Other; and (c) Other treatments in 2014 wound episodes occurring in 861 patients (mean 2.34 wounds/patient).
Jing Yao et al.
International journal of pharmaceutics, 352(1-2), 256-262 (2007-12-07)
The purpose of this study was to characterize the in vitro properties of a number of chitosan-based microemulsions containing nobiletin and determine its distribution in mice brain following i.v. administration. The phase behavior and properties of chitosan-based microemulsions were investigated

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