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313M-1

Sigma-Aldrich

Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody

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1 ML
$124.00
0.1 ML
$170.00
7 ML
$303.00
0.5 ML
$305.00
1 ML
$419.00

$124.00


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1 ML
$124.00
0.1 ML
$170.00
7 ML
$303.00
0.5 ML
$305.00
1 ML
$419.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

$124.00


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Request a Bulk Order

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

AE1 & AE3, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (313M-14)
vial of 0.5 mL concentrate (313M-15)
bottle of 1.0 mL predilute (313M-17)
vial of 1.0 mL concentrate (313M-16)
bottle of 7.0 mL predilute (313M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1κ

control

breast, colon, prostate, skin

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... KRT1(3848)

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This Item
301M-1303M-1MAB3412
species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

chicken, mouse, monkey, human, rabbit, bovine, rat

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

purified antibody

biological source

mouse

biological source

mouse

biological source

mouse

biological source

mouse

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

clone

AE1 & AE3, monoclonal

clone

AE1, monoclonal

clone

AE3, monoclonal

clone

AE1/AE3, monoclonal

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

technique(s)

ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

General description

Anti-cytokeratin cocktail (AE1 & AE3) is a broad-spectrum keratin antibody cocktail. It is composed of mouse monoclonal antibody AE1 that recognizes acidic type I keratins and AE3 that reacts with basic type II keratins. Both clones were generated using epidermal keratin as immunogen. This antibody is useful for identifying cells of epithelial origin and detects most carcinomas of different primarysites. This antibody cocktail can cross-react with other intermediate filaments, such as glialfibrillary acidic protein, giving false-positive staining in glial tumors.

Quality


IVD

IVD

IVD

RUO

Linkage

Cytokeratin Cocktail Positive Control Slides, Product No. 313S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Questions

  1. Is there a broad spectrum CK cocktail that is an equivalent to the Dako MNF116?

    1 answer
    1. The closest to MNF6 (detects CK 5, 6, 8, 17, and possibly 19) is CK cocktail AE1/AE3, which detects all but CK17. Oscar detects CK 7, 8, 18, and 19.

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