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336A-7

Sigma-Aldrich

Synaptophysin Rabbit Polyclonal Antibody

NACRES:
NA.41

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

Ig fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (336A-74)
vial of 0.5 mL concentrate (336A-75)
bottle of 1.0 mL predilute (336A-77)
vial of 1.0 mL concentrate (336A-76)
bottle of 7.0 mL predilute (336A-78)

manufacturer/tradename

Cell Marque

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

control

pancreas

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... SYP(6855)

General description

Anti-synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, Paneth cells in the gastrointestinal tract, and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Anti-synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Linkage

Synaptophysin Positive Control Slides , Product No. 336S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Other Notes

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Legal Information

Cell Marque is a trademark of Sigma-Aldrich Co. LLC

Certificate of Analysis

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Certificate of Origin

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