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336R-9

Synaptophysin (MRQ-40) Rabbit Monoclonal Antibody

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$152.00

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$187.00

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$367.00

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$405.00

1 ML

$589.00

$152.00

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
MRQ-40, monoclonal
Application:
IHC (p)
Species reactivity:
human
Citations:
10
Technique(s):
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-40, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (336R-94), vial of 0.5 mL concentrate (336R-95), bottle of 1.0 mL predilute (336R-97), vial of 1.0 mL concentrate (336R-96), bottle of 7.0 mL predilute (336R-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG1

control

pancreas

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Quality Level

100, 500

Gene Information

human ... SYP(6855)

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This Item
336R-1SAB4200544MAB5258
Synaptophysin (MRQ-40) Rabbit Monoclonal Antibody

Sigma-Aldrich

336R-9

Synaptophysin (MRQ-40) Rabbit Monoclonal Antibody

Synaptophysin (EP158) Rabbit Monoclonal Primary Antibody

Sigma-Aldrich

336R-1

Synaptophysin (EP158) Rabbit Monoclonal Primary Antibody

Anti-Synaptophysin antibody, Mouse monoclonal clone SVP-38, purified from hybridoma cell culture

Sigma-Aldrich

SAB4200544

Anti-Synaptophysin antibody, Mouse monoclonal

Anti-Synaptophysin Antibody, clone SY38 clone SY38, Chemicon®, from mouse

Sigma-Aldrich

MAB5258

Anti-Synaptophysin Antibody, clone SY38

clone

MRQ-40, monoclonal

clone

EP158, monoclonal

clone

SVP-38, monoclonal

clone

SY38, monoclonal

species reactivity

human

species reactivity

human

species reactivity

rat, human

species reactivity

bovine, rat, avian, fish, mouse, human

biological source

rabbit

biological source

rabbit

biological source

mouse

biological source

mouse

antibody form

culture supernatant

antibody form

culture supernatant

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

shipped in

wet ice

Analysis Note


IVD
IVD
IVD
RUO

General description

Anti-synaptophysin reacts with neuroendocrine cells of the human adrenal medulla, pituitary,thyroid, lung, pancreas, and gastrointestinal mucosa. Positive staining is seen in neuronsof the brain. This antibody identifies normal neuroendocrine cells and neuroendocrineneoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probablycorrelates with the distribution of the antigen within neurosecretory vesicles. Antisynaptophysin is an independent, broad-range marker of neural and neuroendocrinedifferentiation.

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]
Synaptophysin Positive Control Slides , Product No. 336S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificates of Analysis (COA)

Lot/Batch Number
0000514530
0000515360
0000514530
0000515360
0000482035

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Yasutaka Yamada et al.
Science translational medicine, 15(722), eadf6732-eadf6732 (2023-11-15)
Aberrant DNA methylation has been implicated as a key driver of prostate cancer lineage plasticity and histologic transformation to neuroendocrine prostate cancer (NEPC). DNA methyltransferases (DNMTs) are highly expressed, and global DNA methylation is dysregulated in NEPC. We identified that
K Kayser et al.
Pathology, research and practice, 183(4), 412-417 (1988-08-01)
The value of immunoreactivity of antibodies against neuronspecific enolase (NSE), bombesin (GRP), and synaptophysin (SY 38) as markers for various human lung carcinoma has been assessed. One hundred-forty-two primary bronchus carcinomas (small cell anaplastic carcinoma, epidermoid carcinoma, adeno carcinoma, and
T Kamisawa et al.
Pathology, research and practice, 192(9), 901-908 (1996-09-01)
To evaluate the significance of neuroendocrine differentiation in duct carcinoma of the pancreas, we investigated 79 pancreatic carcinomas, applying histochemistry and immunohistochemistry (chromogranin A, Leu-7, synaptophysin and neuron-specific enolase (NSE), and correlated the morphologic differentiation pattern with clinicopathological characteristics. There
Michael G Conner et al.
Annals of diagnostic pathology, 6(6), 345-348 (2002-12-13)
Twenty-three patients with primary small cell carcinoma of the uterine cervix are presented. Their ages ranged between 23 and 63 years (average, 43 years). Blood spotting or vaginal bleeding was the most common clinical presentation. Histologically, the tumors were densely
M Skacel et al.
Applied immunohistochemistry & molecular morphology : AIMM, 8(3), 203-209 (2000-09-12)
Histologic differential diagnosis of acinar cell carcinoma (ACC), mixed acinar-endocrine cell carcinoma (MAEC), and pancreatic endocrine tumors (PET) can be difficult but is important because of differences in their clinical behavior. This study investigates the utility of immunohistochemistry (IHC) in
View All Related Papers

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Immunohistochemistry Applications in Gastrointestinal Cancer

Colorectal cancer is the third most common cancer in both men and women. An estimated 136,000 cases of colorectal cancer are expected to occur in 2016.

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