39953

Lauroyl-L-carnitine

≥95.0% (HPLC)

• Synonym(s): (-)-Lauroylcarnitine, dodecanoylcarnitine, (2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxododecyl)oxy]-1-propanaminium inner salt, L-Carnitine dodecanoyl ester, C12-Carnitine, Dodecanoyl-L-carnitine
• Empirical Formula (Hill Notation): C₁₉H₃₇NO₄
• CAS Number: 25518-54-1
• Molecular Weight: 343.50
• Beilstein/REAXYS Number: 4147610
• MDL number: MFCD01743184
• UNSPSC Code: 12352211
• PubChem Substance ID: 329755920
• NACRES: NA.26

Properties

• Quality Level: 100
• assay: ≥95.0% (HPLC)
• form: powder or crystals
• optical activity: [α]/D -20±2°, c = 1 in methanol
• packaging: pkg of 10 mg; pkg of 50 mg
• impurities: ≤10% water
• color: white to off-white
• functional group: ester
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCCCCCCCCCC)=O)CC([O-])=O
• InChI: 1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1
• InChI key: FUJLYHJROOYKRA-QGZVFWFLSA-N

Description

General description

Lauroyl-L-carnitine, or Dodecanoylcarnitine, is an acylcarnitine compound with essential roles in energy metabolism. Synthesized in the liver from methionine, this metabolite of lysine is integral in various metabolic processes, making it a valuable asset in both biochemical and metabolomics research. Its concentration can serve as a diagnostic marker, particularly in cases of carnitine deficiency, and is of significance in assessing disease activity and diagnosing conditions like HIV and chronic hepatitis B infections. Additionally, Lauroyl-L-carnitine is associated with fatty acid oxidation disorders, including long-chain acyl CoA dehydrogenase deficiency and carnitine palmitoyltransferase I/II deficiency, further enhancing its relevance in metabolic research and diagnosis[1]. This acylcarnitine compound has also been detected in cancer tissues, human serum, and tissue biopsies, expanding its applications and potential contributions to various areas of metabolomics research.

Application

Lauroyl-L-carnitine finds application in biochemical research and metabolomics research.

Biochem/physiol Actions

Lauroyl-L-carnitine is an acylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I deficiency, and carnitine palmitoyltransferase II deficiency.

Features and Benefits

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

Other Notes

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable