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MilliporeSigma

40395

α-Carotene

≥95.0% (HPLC)

Synonym(s):

(+)-α-Carotene

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About This Item

Empirical Formula (Hill Notation):
C40H56
CAS Number:
7488-99-5
Molecular Weight:
536.87
Beilstein/REAXYS Number:
3227603
MDL number:
MFCD00136012
UNSPSC Code:
12352202
PubChem Substance ID:
329755985
NACRES:
NA.32

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Quality Level

100

assay

≥95.0% (HPLC)

form

powder

optical purity

enantiomeric excess: ≥95.0%

mp

183-185 °C

λ

2 % in methylene chloride (in hexane)

UV absorption

λ: 445-449 nm Amax

storage temp.

−20°C

SMILES string

CC(/C=C/[C@H]1C(C)=CCCC1(C)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(\C=C\C2=C(C)CCCC2(C)C)C

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-23,25-28,37H,15-16,24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+/t37-/m0/s1

InChI key

ANVAOWXLWRTKGA-NTXLUARGSA-N

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Show Differences

1 of 4

This Item
742835088752824
α-Carotene ≥95.0% (HPLC)

Sigma-Aldrich

40395

α-Carotene

(±)-α-Carotene ≥95.0% (HPLC)

Sigma-Aldrich

74283

(±)-α-Carotene

α-Carotene analytical standard

Supelco

50887

α-Carotene

(9Z)-β-Carotene ≥90.0% (HPLC)

Sigma-Aldrich

52824

(9Z)-β-Carotene

assay

≥95.0% (HPLC)

assay

≥95.0% (HPLC)

assay

≥97.0% (HPLC)

assay

≥90.0% (HPLC)

form

powder

form

powder

form

-

form

solid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

mp

183-185 °C

mp

-

mp

183-185 °C

mp

-

optical purity

enantiomeric excess: ≥95.0%

optical purity

-

optical purity

-

optical purity

-

General description

Carotenoids are natural products used in the food, animal feed, nutraceutical, and pharmaceutical industries.[1] α-Carotene, a carotenoid with one β-ring and one ε-ring,[1] is commonly present in the food. Orange carrots show a high concentration of α-carotene.[2]

Application

α-Carotene may be used as a standard in high-performance liquid chromatography (HPLC) for carotenoid quantification in Corynebacterium glutamicum.[1]

Biochem/physiol Actions

α-Carotene exhibits provitamin A activity.[2] It can act as an efficient inhibitor than β-carotene on certain growth factors, like N-myc activity. α-Carotene serves as a good biomarker for fruit and vegetable consumption.[3] High serum concentrations of α-carotene are associated with lower cardiovascular disease (CVD) mortality.[4]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN9211
BCCN3919
BCCM1577
BCCM1576
BCCL0438

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Sebastiaan Bijttebier et al.
Journal of chromatography. A, 1332, 46-56 (2014-02-19)
Aim of study was to find the most suitable LC column for generic carotenoid screening. To represent the diversity of carotenoids in nature and to optimize chromatographic separation, a set of carotenoid standards was carefully chosen to account for the
K J Yeum et al.
The American journal of clinical nutrition, 64(4), 594-602 (1996-10-01)
Plasma carotenoid responses were determined in 36 healthy men and women before and after being fed controlled diets with a moderate amount of fat (26% of total energy) and a high carotenoid content (approximately 16 mg/d) for two 15-d periods.
Louise M Canfield et al.
European journal of nutrition, 42(3), 133-141 (2003-06-18)
Carotenoids in serum vary between countries and within populations with evidence suggesting a qualitative relationship to diet. Breast milk carotenoids furnish a source of vitamin A and potentially provide immunoprotection and other health benefits for infants. There have been numerous
Overview of the Role of Antioxidant Vitamins as Protection Against Cardiovascular Disease: Implications for Aging
Aging null
Carotenoids: health effects
OPTO-Ireland. International Society for Optics and Photonics (2013)
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