If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf
43819
DL-Dithiothreitol
≥99.0% (RT)
Synonym(s):
threo-1,4-Dimercapto-2,3-butanediol, Cleland’s reagent, DTT
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assay
≥99.0% (RT)
form
powder
reaction suitability
reagent type: reductant
impurities
≤0.3% 4,5-dihydroxy-1,2-dithiane
mp
40-43 °C
41-44 °C (lit.)
solubility
H2O: 50 mg/mL, clear, colorless
H2O: freely soluble
acetone: freely soluble
chloroform: freely soluble
diethyl ether: freely soluble
ethanol: freely soluble
ethyl acetate: freely soluble
anion traces
sulfate (SO42-): ≤50 mg/kg
cation traces
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤250 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
storage temp.
2-8°C
SMILES string
O[C@H](CS)[C@H](O)CS
InChI
1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
InChI key
VHJLVAABSRFDPM-QWWZWVQMSA-N
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This Item | D0632 | D5545 | D9779 |
|---|---|---|---|
| assay ≥99.0% (RT) | assay ≥98% (HPLC), ≥99.0% (titration) | assay ≥99.0% (titration) | assay ≥98% (HPLC), ≥99% (titration) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| mp 40-43 °C, 41-44 °C (lit.) | mp 41-44 °C (lit.) | mp 41-44 °C (lit.) | mp 41-44 °C (lit.) |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| impurities ≤0.3% 4,5-dihydroxy-1,2-dithiane | impurities - | impurities Insoluble matter, passes filter test, ≤0.3% 4,5-dihydroxy-1,2-dithiane | impurities - |
| solubility H2O: 50 mg/mL, clear, colorless, acetone: freely soluble, diethyl ether: freely soluble, ethyl acetate: freely soluble, H2O: freely soluble, ethanol: freely soluble, chloroform: freely soluble | solubility H2O: soluble 50 mg/mL, clear, colorless to very faintly yellow | solubility H2O: 0.1 M, clear, colorless | solubility H2O: 50 mg/mL |
Application
Biochem/physiol Actions
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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