45124
Elastase from porcine pancreas
powder, white, ≥10 U/mg
Synonym(s):
Elastase from hog pancreas, Pancreatopeptidase E
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About This Item
CAS Number:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
254-453-6
MDL number:
Specific activity:
≥10 U/mg
Biological source:
Porcine pancreas
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biological source
Porcine pancreas
form
powder
specific activity
≥10 U/mg
mol wt
Mr ~25000
color
white
storage temp.
−20°C
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Biochem/physiol Actions
Elastase hydrolyses elastin, the specific protein of elastic fibers, and digests hemoglobin, casein and fibrin.
Other Notes
1 U corresponds to the amount of enzyme which liberates 1 μmol 4-nitroaniline per minute at 25°C and pH 7.8 (succinyl-(L-Ala)3-4-nitroanilide as substrate)
Cleaves polyalanyl-lysine peptides at the alanyl-lysine bond, review[1]; Review, elastase-type proteases[2][3]
One unit will hydrolyze 1.0 μmole of N-succinyl-L-Ala-Ala-Ala-p-nitroanilide per min, pH 8.0 at 25 °C.
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D. Atlas et al.
Proc. 13th Eur. Pept. Symp.: Peptides 1974, 361-361 (1975)
Huanlei Zhu et al.
International journal of clinical and experimental pathology, 12(4), 1260-1271 (2020-01-15)
The formation and rupture of aneurysms is a reversible process involving the destruction and repair of smooth muscle cells, and the proliferation of vascular smooth muscle cells (VSMC) and inflammation play an important role. In our study, we investigated whether
L Robert
Pathologie-biologie, 36(9), 1101-1107 (1988-11-01)
Elastin in the most resistant fibrous protein of the organisms. Its degradation is catalysed by proteases designated as elastases. Elastic fibers appeared during phylogenesis at the level of the first Vertebrates and rendered possible the emergence of efficient circulatory and
Hee-Jeong Choi et al.
Oxidative medicine and cellular longevity, 2020, 2905362-2905362 (2020-07-21)
Ultraviolet B (UVB) irradiation is major causative factor in skin aging. The aim of the present study was to investigate the protective effect of a 50% ethanol extract from Nypa fruticans (NF50E) against UVB-induced skin aging. The results indicated that
Baumstark, J.S., et al.
Biochimica et Biophysica Acta, 77, 676-676 (1963)
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