46051

Sigma-Aldrich

Esterase from Bacillus stearothermophilus

≥0.2 U/mg

CAS Number:
Enzyme Commission number:
EC Number:
MDL number:
NACRES:
NA.54
Pricing and availability is not currently available.

Quality Level

form

lyophilized

specific activity

≥0.2 U/mg

storage temp.

2-8°C

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Application

The compound is commonly used for the synthesis of biodiesel and biopolymers, as well as in the production of pharmaceuticals, agrochemicals and flavor compounds.

Biochem/physiol Actions

Esterase acts on water-soluble carboxyl esters containing short chain fatty acids .
The esterase catalyzes the transesterification of 1-phenylethanol.

Unit Definition

1 U corresponds to the amount of enzyme which releases 1 μmol 4-nitrophenol per minute at pH 7.0 and 65°C (4-nitrophenyl-n-octanoate as substrate)

Other Notes

Heat stable enzyme

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
D.A. Cowan
Enzyme and Microbial Technology, 12, 374-374 (1990)
Marie C Fortin et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(2), 326-331 (2012-12-12)
Studies on therapeutic drug disposition in humans have shown significant alterations as the result of pregnancy. However, it is not known whether pesticide metabolic capacity changes throughout pregnancy, which could affect exposure of the developing brain. We sought to determine...
Joshua P Lewis et al.
Pharmacogenetics and genomics, 23(1), 1-8 (2012-11-01)
Carboxylesterase 1 (CES1) is the primary enzyme responsible for converting clopidogrel into biologically inactive carboxylic acid metabolites. We genotyped a functional variant in CES1, G143E, in participants of the Pharmacogenomics of Anti-Platelet Intervention (PAPI) study (n=566) and in 350 patients...
Edite Cunha et al.
Journal of hazardous materials, 244-245, 563-569 (2012-12-19)
Aiming the prediction of ionic liquids' (ILs) human toxicity, an automated carboxylesterase activity assay was developed. The method was implemented on a sequential injection analysis (SIA) system and relied on the hydrolysis of 4-methylumbelliferyl acetate by the enzyme, to produce...
Sascha Obrowsky et al.
Journal of lipid research, 54(2), 425-435 (2012-12-12)
Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme mediating triglyceride (TG) hydrolysis. The lack of ATGL results in TG accumulation in multiple tissues, underscoring the critical role of ATGL in maintaining lipid homeostasis. Recent evidence suggests that ATGL affects TG...

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