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46943

Sigma-Aldrich

Fluorescein dilaurate

suitable for fluorescence, ≥97.0% (HPCE)

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Empirical Formula (Hill Notation):
C44H56O7
CAS Number:
Molecular Weight:
696.91
Beilstein/REAXYS Number:
6034843
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.32

assay

≥97.0% (HPCE)

form

powder

solubility

ethanol: soluble

fluorescence

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

suitability

suitable for fluorescence

SMILES string

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3

InChI key

MYTRGBGGRICZGN-UHFFFAOYSA-N

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1 of 4

This Item
469354696036799
vibrant-m

46943

Fluorescein dilaurate

vibrant-m

46960

Fluorescein sodium salt

fluorescence

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

fluorescence

λex 491 nm; λem 515 nm in 0.1 M Tris pH 9.0

fluorescence

λex 460 nm; λem 515 nm(lit.), λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0

fluorescence

λex 409 nm; λem 473 nm in 0.1 M Tris pH 9.0

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

solubility

ethanol: soluble

solubility

DMF: soluble, DMSO: soluble

solubility

-

solubility

DMF: soluble, DMSO: soluble

assay

≥97.0% (HPCE)

assay

≥90% (HPCE)

assay

-

assay

≥98.0% (HPCE)

form

powder

form

solid

form

powder

form

-

Application

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
E Małecka-Panas et al.
Polskie Archiwum Medycyny Wewnetrznej, 94(4), 315-323 (1995-10-01)
The aim of the presented study was a comparative evaluation of the three indirect pancreatic function tests: pancreolauryl-test (PLT), NBT-PABA test and faecal chymotrypsin (CH) efficacy in detecting pancreatic exocrine function impairment in advanced chronic pancreatitis (acp). 30 patients with
Z Wójcik et al.
Polski tygodnik lekarski (Warsaw, Poland : 1960), 50(1-35), 791-793 (1995-01-01)
Fifteen patients with chronic pancreatitis were qualified for surgical treatment on the basis of the results of endoscopic retrograde cholangiopancreatography, pancreolauryl test and glucose tolerance test. Significant changes according to Cambridge scale correlated with exocrine-endocrine pancreatic failure. In patients with
A L Trewick
Annals of clinical biochemistry, 35 ( Pt 2), 274-278 (1998-04-21)
The influence of the glucose concentration in urines being assayed as part of a pancreolauryl test was investigated. Paired patient urines (n = 5) were assayed at 60 degrees and 70 degrees C, before and after spiking to 5% glucose.
Maria Beatriz Di Carlo et al.
Acta gastroenterologica Latinoamericana, 40(2), 128-133 (2010-07-22)
The pancreas is a mixed gland that takes part in the digestion of nutrients and in the homeostasis ofglycemia. Chronic pancreopathy is the cause of secretory insufficiency, characterized by an inflammatory process that leads to fibrosis of the pancreas, with

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