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47036

Sigma-Aldrich

Saponin

for molecular biology, used as non-ionic surfactant

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Synonym(s):
Glycosides, Saponins
CAS Number:
EC Number:
MDL number:
NACRES:
NA.25

grade

for molecular biology

mol wt

1000-2000 g/mol

composition

Sapogenin, 8-25%

technique(s)

HPLC: suitable
protein quantification: suitable

CMC

0.001-0.01%

density

1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)

foreign activity

DNase, RNase, Protease, Phosphatase, none detected

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This Item
S7900S452184510
Sigma-Aldrich

Sigma-Aldrich

47036

Saponin

Saponin Quillaja sp. Sapogenin content 20-35 %

Sigma-Aldrich

S4521

Saponin Quillaja sp.

Saponin used as non-ionic surfactant

Sigma-Aldrich

84510

Saponin

mol wt

1000-2000 g/mol

mol wt

-

mol wt

-

mol wt

-

technique(s)

HPLC: suitable, protein quantification: suitable

technique(s)

HPLC: suitable, protein quantification: suitable

technique(s)

HPLC: suitable, protein quantification: suitable

technique(s)

HPLC: suitable, protein quantification: suitable

CMC

0.001-0.01%

CMC

-

CMC

-

CMC

0.001-0.01%

density

1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)

density

-

density

-

density

1.015-1.020 g/mL at 20 °C (5% in H2O)(lit.)

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

300

General description

Saponins are a large family of amphiphilic glycosides of steroids and triterpenes. Saponins are found in many plants and are localized especially in the root, tuber, bark, leaves, seed, and fruit. They are also present in some animals, like sea cucumber.

Application

Saponin has been used:
  • in phosphate-buffered saline (PBS) to block cells for immunocytochemistry and confocal microscopy
  • to permeabilize cells for measuring total mitochondrial mass
  • as an internal control to extract saponin Holothuria nobilis Selenka

Glycoside used as a nonionic sufactant and adjuvant in vaccine development.

Biochem/physiol Actions

Saponins are nonionic surfactant that forms oil-in-water emulsions and acts as a protective colloid. They are used for the direct determination of metals in milk by flame atomic absorption spectrophotometry.
Saponins exhibit anti-tumor, antimicrobial, and anti-herbivore activity. They may also play a key role in plant defense. Saponins also possess several pharmaceutical properties, like anti-inflammatory, antifungal, antibacterial, anti-parasitic, and antiviral activities. Saponins can regulate rhizosphere bacteria in the soil.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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