50359

Voglibose

≥97.0% (TLC)

• Synonym(s): 3,4-Dideoxy-4-{[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-D-epi-inositol, N-(1,3-Dihydroxyprop-2-yl)valiolamine
• Empirical Formula (Hill Notation): C₁₀H₂₁NO₇
• CAS Number: 83480-29-9
• Molecular Weight: 267.28
• MDL number: MFCD00865496
• PubChem Substance ID: 329757591
• NACRES: NA.25

Properties

• biological source: synthetic
• Quality Level: 100
• Assay: ≥97.0% (TLC)
• storage temp.: −20°C
• SMILES string: OCC(CO)N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O
• InChI: 1S/C10H21NO7/c12-2-5(3-13)11-6-1-10(18,4-14)9(17)8(16)7(6)15/h5-9,11-18H,1-4H2/t6-,7-,8+,9-,10-/m0/s1
• InChI key: FZNCGRZWXLXZSZ-CIQUZCHMSA-N
• Gene Information: human ... GAA(2548) , MGAM(8972) , MGAM2(93432) , SI(6476)

Description

Application

Voglibose is an α-glucosidase inhibitor, similar to acarbose and miglitol, used for lowering post-prandial hyperglycemia (PPHG) in people with diabetes mellitus. Voglibose is used to study it benefits as a protectant against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves