MilliporeSigma
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57000

Sigma-Aldrich

Indigo carmine

for microscopy (Bact., Hist.), indicator (pH 11.5-14.0)

Synonym(s):
Indigo-5,5′-disulfonic acid disodium salt, Indigocarmine, Acid Blue 74
Empirical Formula (Hill Notation):
C16H8N2Na2O8S2
CAS Number:
Molecular Weight:
466.35
Colour Index Number:
73015
Beilstein:
4103904
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.47

grade

for microscopy (Bact., Hist.)
indicator (pH 11.5-14.0)

form

powder

loss

≤5% loss on drying

pH

3.87 (30 °C, 7.14 g/L)

mp

>340 °C

solubility

methanol: 0.01 g/10 mL, blue to very deep blue

density

0.71 g/cm3 at 29 °C

εmax

≥350 at 603-613 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O

InChI

1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;

InChI key

KHLVKKOJDHCJMG-QDBORUFSSA-L

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Application

Indigo carmine has been used in agarose plates to study behavioral feeding assays in Drosophila larvae. It has also been used for macroscopic assessment of intestinal adenomatous polyps isolated from mice.

Biochem/physiol Actions

Indigo carmine is a contrast dye which helps in highlighting mucosal changes. It accumulates in crevices, cysts and foveolae and stains the tissue blue. The abnormal tissue remains translucent pink.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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More documents

Quotes and Ordering

Endoscopic Imaging Techniques and Tools (2006)
CDC42 inhibition suppresses progression of incipient intestinal tumors.
Sakamori R, et al.
Cancer Research, 74, 5480-5480 (2014)
A Pair of Pharyngeal Gustatory Receptor Neurons Regulates Caffeine-Dependent Ingestion in Drosophila Larvae.
Choi J, et al.
Frontiers in Cellular Neuroscience, 10, 181-181 (2016)
Aurora rings: a novel endoscopic finding to distinguish inverted colonic diverticula from colon polyps.
Michael D Share et al.
Gastrointestinal endoscopy, 77(2), 308-312 (2012-12-05)
Three-dimensional staining of liver segments with an ultrasound contrast agent as an aid to anatomic liver resection.
Junichi Shindoh et al.
Journal of the American College of Surgeons, 215(2), e5-10 (2012-06-12)

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