57400

Sigma-Aldrich

Indole-3-propionic acid

≥99.0% (T)

Synonym(s):
IPA, NSC 47831, 3-(3-Indolyl)propanoic acid, NSC 3252, 3-(3-Indolyl)propionic acid
Empirical Formula (Hill Notation):
C11H11NO2
CAS Number:
Molecular Weight:
189.21
Beilstein/REAXYS Number:
147733
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

Quality Level

assay

≥99.0% (T)

ign. residue

≤0.1%

mp

~133 °C

SMILES string

OC(=O)CCc1c[nH]c2ccccc12

InChI

1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14)

InChI key

GOLXRNDWAUTYKT-UHFFFAOYSA-N

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Biochem/physiol Actions

Studied as an adjunct to improve perfusion after liver transplant.

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Zhongqi Cheng et al.
Environmental science & technology, 39(19), 7662-7666 (2005-10-26)
Field and laboratory experiments were conducted to study the potential use of Fe filings to remove monomethyl arsenate (MMA) and dimethyl arsenate (DMA) from contaminated waters. Batch experiments show that the affinity of MMAfor Fe filings is comparable to that...
Shardulendra P Sherchand et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(25), 12468-12477 (2019-05-18)
A striking difference between genital and ocular clinical isolates of Chlamydia trachomatis is that only the former express a functional tryptophan synthase and therefore can synthesize tryptophan by indole salvage. Ocular isolates uniformly cannot use indole due to inactivating mutations...
Andrew W Woodward et al.
Plant physiology, 144(2), 976-987 (2007-04-24)
The ubiquitin-like protein RELATED TO UBIQUITIN (RUB) is conjugated to CULLIN (CUL) proteins to modulate the activity of Skp1-Cullin-F-box (SCF) ubiquitylation complexes. RUB conjugation to specific target proteins is necessary for the development of many organisms, including Arabidopsis (Arabidopsis thaliana)....
Stéphanie Ortial et al.
Journal of medicinal chemistry, 49(9), 2812-2820 (2006-04-28)
The use of classical antioxidants is limited by their low bioavailabilities, and therefore, high doses are usually required to display significant protective activity. In a recent article (J. Med. Chem. 2003, 46, 5230) we showed that the ability of the...
Y J Chyan et al.
The Journal of biological chemistry, 274(31), 21937-21942 (1999-07-27)
Widespread cerebral deposition of a 40-43-amino acid peptide called the amyloid beta-protein (Abeta) in the form of amyloid fibrils is one of the most prominent neuropathologic features of Alzheimer's disease. Numerous studies suggest that Abeta is toxic to neurons by...

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