Interleukin-2 human

recombinant, expressed in E. coli, ~10000 U/mL

IL-2, hIL-2, TCGF
CAS Number:
MDL number:

Quality Level

biological source



expressed in E. coli



mol wt

Mr ~15500


vial of 1 mL


~10000 U/mL



UniProt accession no.

shipped in

dry ice

storage temp.


Gene Information

human ... IL2(3558)

Biochem/physiol Actions

Promotes the growth of IL-2 dependent lymphocytes. Amino acid sequence of IL-2.


One vial contains 10′000 Units


Stable at −20 °C; prepare appropriate aliquots and avoid repeated freezing and thawing, since aggregation may occur resulting in apparent loss of activity.

Unit Definition

1 U corresponds to the unit activity in the colorimetric MTT-assay with CTLL-2 cells.

Physical form

Clear; colorless solution in Dulbecco-PBS; containing 1 mg BSA/mL.

Other Notes

Sales restrictions may apply.


12 - Non Combustible Liquids

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

S Gillis et al.
Journal of immunology (Baltimore, Md. : 1950), 120(6), 2027-2032 (1978-06-01)
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes. One of these factors present in medium conditioned by T cell mitogen-stimulated lymphocytes has the ability to promote the long-term culture of normal and antigen-specific...
Interleukin 2.
K A Smith
Annual review of immunology, 2, 319-333 (1984-01-01)
R J Robb et al.
Proceedings of the National Academy of Sciences of the United States of America, 81(20), 6486-6490 (1984-10-01)
Human interleukin 2 was separated into multiple molecular forms by selective immunoaffinity chromatography and chromatofocusing. For the most part, this heterogeneity was attributed to variations in glycosylation of the threonine residue in position 3 of the polypeptide chain. The various...
Denise L Cecil et al.
Cancer research, 74(10), 2710-2718 (2014-04-30)
Immunization against self-tumor antigens can induce T-regulatory cells, which inhibit proliferation of type I CD4(+) T-helper (TH1) and CD8(+) cytotoxic T cells. Type I T cells are required for potent antitumor immunity. We questioned whether immunosuppressive epitopes could be identified...
Katrien Van Raemdonck et al.
Angiogenesis, 17(3), 631-640 (2014-01-29)
CXC chemokines influence a variety of biological processes, such as angiogenesis, both in a physiological and pathological context. Platelet factor-4 (PF-4)/CXCL4 and its variant PF-4var/CXCL4L1 are known to favor angiostasis by inhibiting endothelial cell proliferation and chemotaxis. CXCL4L1 in particular...

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service