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MilliporeSigma

60178

Potassium cyanide

BioUltra, ≥98.0% (AT)

Synonym(s):

KCN, Potassium salt of hydrocyanic acid

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25 G

$45.20

100 G

$152.00

$45.20


Estimated to ship onJanuary 23, 2026Details


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About This Item

Linear Formula:
KCN
CAS Number:
Molecular Weight:
65.12
UNSPSC Code:
12352302
NACRES:
NA.25
PubChem Substance ID:
EC Number:
205-792-3
Beilstein/REAXYS Number:
3593645
MDL number:

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Product Name

Potassium cyanide, BioUltra, ≥98.0% (AT)

InChI key

YUZRZFQHUCKACF-UHFFFAOYSA-N

InChI

1S/CN.K/c1-2;

SMILES string

[K]C#N

biological source

synthetic

product line

BioUltra

assay

≥98.0% (AT)

form

crystalline

impurities

insoluble matter, passes filter test

pH

11.0-13.0 (25 °C, 1 M in H2O)

mp

634 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

anion traces

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤400 mg/kg
sulfide (S2-): ≤5 mg/kg
thiocyanate (SCN-): ≤100 mg/kg

cation traces

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤100 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤5000 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

UV absorption

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

Quality Level

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1 of 4

This Item
1.0496511813207810
assay

≥98.0% (AT)

assay

≥96% (silver nitrate titration)

assay

≥96%

assay

≥96.0%

biological source

synthetic

biological source

-

biological source

-

biological source

-

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

form

crystalline

form

solid

form

solid

form

granular

solubility

H2O: 1 M at 20 °C, clear, colorless

solubility

-

solubility

-

solubility

water: soluble(lit.)

mp

634 °C (lit.)

mp

634 °C

mp

634 °C (lit.)

mp

634 °C (lit.)

Application

Potassium cyanide is use to inhibit oxidative phosphorylation reactions in a wide variety of biological systems and applications.

Other Notes

Blocks electron transport to oxygen via cytochrome oxidase, hence employed in the determination of succinate dehydrogenase in submitochondrial particles by preventing substantial loss of succinate by electron flux to O2[1][2]

signalword

Danger

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

target_organs

Thyroid

supp_hazards

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Mammalian succinate dehydrogenase.
B A Ackrell et al.
Methods in enzymology, 53, 466-483 (1978-01-01)
Pascaline Clerc et al.
Journal of bioenergetics and biomembranes, 39(2), 158-166 (2007-04-21)
We have studied the effect of nitric oxide (NO) and potassium cyanide (KCN) on oxidative phosphorylation efficiency. Concentrations of NO or KCN that decrease resting oxygen consumption by 10-20% increased oxidative phosphorylation efficiency in mitochondria oxidizing succinate or palmitoyl-L-carnitine, but
EPR and other properties of succinate dehydrogenase.
T Ohnishi et al.
Methods in enzymology, 53, 483-495 (1978-01-01)
Yudong Wang et al.
The Journal of biological chemistry, 285(39), 29834-29841 (2010-07-29)
Fatty acid β-oxidation (FAO) and oxidative phosphorylation (OXPHOS) are key pathways involved in cellular energetics. Reducing equivalents from FAO enter OXPHOS at the level of complexes I and III. Genetic disorders of FAO and OXPHOS are among the most frequent
Chunhua Jiang et al.
Frontiers in cell and developmental biology, 8, 603688-603688 (2021-01-08)
Arginyltransferase 1 (ATE1) is an evolutionary-conserved eukaryotic protein that localizes to the cytosol and nucleus. It is the only known enzyme in metazoans and fungi that catalyzes posttranslational arginylation. Lack of arginylation has been linked to an array of human

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. Hello, please can this type be used for laboratory experiments on experimental rodents 

    1 answer
    1. Product No. 60178 is not intended for live animal testing.

      Helpful?

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