70215

Sigma-Aldrich

2,3-Naphthalenedicarboxaldehyde

suitable for fluorescence

Synonym(s):
NDA
Linear Formula:
C10H6(CHO)2
CAS Number:
Molecular Weight:
184.19
Beilstein/REAXYS Number:
2207267
MDL number:
PubChem Substance ID:

Quality Level

impurities

≤2% mono- and dicarboxylic acid (1H-NMR)

mp

131-133 °C (lit.)
132-135 °C

fluorescence

λex 420 nm; λem ~480 nm in 0.1 M borate pH 9.3 (after derivatization with glycine [~90 μM glycine, ~20 μM N-])

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

[H]C(=O)c1cc2ccccc2cc1C([H])=O

InChI

1S/C12H8O2/c13-7-11-5-9-3-1-2-4-10(9)6-12(11)8-14/h1-8H

InChI key

ZIPLKLQPLOWLTM-UHFFFAOYSA-N

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Packaging

500 mg in poly tube
100 mg in poly bottle

Application

Fluorogenic derivatizing agent for amines. NDA conjugates are more stable with stronger fluorescence (λEx 420 nm, λEm 490 nm) than phthaldialdehyde (OPA) conjugates.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
P. de Montigny et al.
Analytical Chemistry, 59, 1096-1096 (1987)
An improved mechanism-based cross-linker for multiplexed kinase detection and inhibition in a complex proteome.
Kai Liu et al.
Chembiochem : a European journal of chemical biology, 9(12), 1883-1888 (2008-07-16)
Richard C Kevin et al.
Forensic toxicology, 37(1), 17-26 (2019-02-02)
The use of novel synthetic cannabinoids as intoxicants continues in spite of associated health risks. These compounds are typically smoked or vaporized, but many synthetic cannabinoids contain thermally labile chemical moieties. This study investigated the thermal stability six carboxamide-type synthetic...
Pradyot Nandi et al.
Electrophoresis, 31(8), 1414-1422 (2010-04-02)
A PDMS-based microfluidic system for online coupling of microdialysis sampling to microchip electrophoresis with fluorescence detection for in vivo analysis of amino acid neurotransmitters using naphthalene-2,3-dicarboxaldehyde and sodium cyanide as the derivatization reagents is described. Fabricating chips from PDMS rather...
T. Ueda et al.
Analytical Chemistry, 63, 2979-2979 (1991)

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