form
powder
loss
~5% loss on drying, 20 °C (HV)
solubility
H2O: 0.1 g/mL, clear to turbid, brown-yellow (hot)
storage temp.
2-8°C
Quality Level
Related Categories
1 of 4
This Item | P2256 | 11715 | 132101 |
|---|---|---|---|
| form powder | form powder | form - | form powder |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. - | storage temp. - |
| solubility H2O: 0.1 g/mL, clear to turbid, brown-yellow (hot) | solubility H2O: 100 mg/mL, clear, colorless to faintly yellow | solubility hot water: soluble 0.2 g/10 mL, clear, colorless | solubility - |
| loss ~5% loss on drying, 20 °C (HV) | loss ≤0.5% loss on drying | loss - | loss - |
Application
<ul>
<li><strong>Tetrahydrophthalazine derivative "sodium nucleinate" exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes:</strong> Describes the anti-inflammatory capabilities of Sodium nucleinate, particularly its ability to inhibit oxidative burst in human monocytes, suggesting its use in anti-inflammatory therapies (Jukic et al., 2012).</li>
<li><strong>A tetrahydrophthalazine derivative ′sodium nucleinate′ exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo:</strong> Outlines the suppressive effects of Sodium nucleinate on LPS-stimulated mononuclear cells, underlining its potential utility in controlling inflammatory responses (Jukic et al., 2011).</li>
</ul>
<li><strong>Tetrahydrophthalazine derivative "sodium nucleinate" exert its anti-inflammatory effects through inhibition of oxidative burst in human monocytes:</strong> Describes the anti-inflammatory capabilities of Sodium nucleinate, particularly its ability to inhibit oxidative burst in human monocytes, suggesting its use in anti-inflammatory therapies (Jukic et al., 2012).</li>
<li><strong>A tetrahydrophthalazine derivative ′sodium nucleinate′ exerts a potent suppressive effect upon LPS-stimulated mononuclear cells in vitro and in vivo:</strong> Outlines the suppressive effects of Sodium nucleinate on LPS-stimulated mononuclear cells, underlining its potential utility in controlling inflammatory responses (Jukic et al., 2011).</li>
</ul>
Biochem/physiol Actions
Sodium nucleinate (SN) serves as an immunomodulatory substance, that possess anti-inflammatory effects.[1]
General description
Sodium nucleinate is a derivative of tetrahydrophthalazine.[1]
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Tetrahydrophthalazine Derivative
Jukic T, et al.
Collegium Antropologicum, 36(2), 409-412 (2012)
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