BioReagent, suitable for fluorescence, ≥97.0% (HPLC)

9-([E]-2-Carboxy-2-cyanovinyl)julolidine, CCVJ
Empirical Formula (Hill Notation):
CAS Number:
Molecular Weight:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

Quality Level

product line



≥97.0% (HPLC)


DMSO: soluble
chloroform: soluble


λex 433 nm; λem 500 nm in 50 mM Tris pH 8.0; 40% glycerol


suitable for fluorescence

SMILES string




InChI key


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Fluorescent probe for binding to proteins etc., quantum yield increases by decreasing free rotation: fluorescent molecular rotor.


Bottomless glass bottle. Contents are inside inserted fused cone.

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Christopher Rumble et al.
The journal of physical chemistry. A, 116(44), 10786-10792 (2012-10-27)
The photochemistry of the rotor probe 9-(2-carboxy-2-cyanovinyl)julolidine (CCVJ) was studied to elucidate a curious effect of fluid flow previously reported. The apparent sensitivity to fluid motion observed in CCVJ but not in the closely related molecule 9-(dicyanovinyl)julolidine (DCVJ) is found...
Elisabeth Ablinger et al.
International journal of pharmaceutics, 441(1-2), 255-260 (2012-12-04)
A differential scanning fluorimetry (DSF) based high-throughput screening assay with the fluorescent molecular rotor CCVJ (9-(2-carboxy-2-cyanovinyl)julolidine) was developed. CCVJ is mainly sensitive to viscosity and less to polarity in comparison to polarity-sensitive dyes like SYPRO Orange, which was commonly used...
James A Levitt et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 12(3), 662-672 (2011-02-18)
We present polarization-resolved fluorescence measurements of fluorescent molecular rotors 9-(2-carboxy-2-cyanovinyl)julolidine (CCVJ), 9-(2,2-dicyanovinyl)julolidine (DCVJ), and a meso-substituted boron dipyrromethene (BODIPY-C(12)). The photophysical properties of these molecules are highly dependent on the viscosity of the surrounding solvent. The relationship between their quantum...
Xingyun Peng et al.
Carbohydrate polymers, 250, 116859-116859 (2020-10-15)
Fluorescence emissions of molecular rotors (MRs) are affected by local restrictions to molecular motion, and therefore it was considered that MRs can be used as structural probes of biopolymers. In this study, 9-(2-carboxy-2-cyanovinyl)-julolidine (CCVJ), a hydrophilic MR, was used to...
Sagar Satpathi et al.
Organic & biomolecular chemistry, 17(21), 5392-5399 (2019-05-21)
Here, we have explored the light-up property of coumarin 343 (C343) selectively towards various i-motif DNAs based on the recognition of hemi-protonated cytosine-cytosine base pairing, unlike other DNA structures. We have also demonstrated the versatile ability of this i-motif ligand...

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