72715

Glutaryl-L-carnitine lithium salt

≥98.0% (TLC)

• Synonym(s): L-Carnitine lithium glutarate
• Empirical Formula (Hill Notation): C₁₂H₂₁NO₆ · xLi⁺
• CAS Number: 102636-82-8
• Molecular Weight: 275.30 (free acid basis)
• PubChem Substance ID: 329764299
• NACRES: NA.25

Properties

• Quality Level: 100
• Assay: ≥98.0% (TLC)
• form: solid
• optical activity: [α]/D -20±2°, c = 1 in H₂O
• impurities: ≤10% water
• color: white to off-white
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCCC(O)=O)=O)CC([O-])=O.C
• InChI: 1S/C12H21NO6/c1-13(2,3)8-9(7-11(16)17)19-12(18)6-4-5-10(14)15/h9H,4-8H2,1-3H3,(H-,14,15,16,17)/t9-/m1/s1
• InChI key: NXJAXUYOQLTISD-SECBINFHSA-N

Description

Biochem/physiol Actions

Increased formation and excretion of glutarylcarnitin results from a glutaryl-CoA dehydrogenase deficiency, an inborn error of lysine and tryptophan metabolism. Secondary carnitine depletion due to increased formation and urinary excretion of glutarylcarnitine is suggested to play an important role in the neuropathogenesis of glutaryl-CoA dehydrogenase deficiency, inducing excitotoxic neuronal damage and mitochondrial dysfunction.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable