Skip to Content
MilliporeSigma

73677

4-Nitrophenyl β-D-glucuronide

β-glucuronidase substrate, chromogenic, ≥99.0% (TLC), powder or crystals, suitable as substrate for β-glucuronidase test

Synonym(s):

4-Nitrophenyl-β-D-glucopyranosiduronic acid, PNPG

Slide 1 of 1
Sign In to View Organizational & Contract Pricing

Select a Size

250 MG

$303.00

1 G

$952.00

$303.00

Available to ship TODAYDetails

About This Item

Empirical Formula (Hill Notation):
C12H13NO9
CAS Number:
10344-94-2
Molecular Weight:
315.23
Beilstein/REAXYS Number:
1438576
EC Number:
233-753-0
MDL number:
MFCD00036210
UNSPSC Code:
12352204
PubChem Substance ID:
57652486
NACRES:
NA.32

Key Documents

View All Documentation

Skip To

Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

4-Nitrophenyl β-D-glucuronide, ≥99.0% (TLC)

Quality Level

200

assay

≥99.0% (TLC)

form

powder or crystals

optical activity

[α]20/D −102±3°, c = 1% in ethanol

impurities

≤0.05% free 4-nitrophenol
≤7% water

solubility

H2O: 0.1 g/mL, clear, faintly yellow

suitability

suitable as substrate for β-glucuronidase test

storage temp.

−20°C

SMILES string

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1

InChI key

QSUILVWOWLUOEU-GOVZDWNOSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
N1627N7006N9376
4-Nitrophenyl β-D-glucuronide ≥99.0% (TLC)

Sigma-Aldrich

73677

4-Nitrophenyl β-D-glucuronide

4-Nitrophenyl β-D-glucuronide ≥98% (TLC)

Sigma-Aldrich

N1627

4-Nitrophenyl β-D-glucuronide

4-Nitrophenyl β-D-glucopyranoside ≥98% (TLC)

Sigma-Aldrich

N7006

4-Nitrophenyl β-D-glucopyranoside

4-Nitrophenyl N-acetyl-β-D-glucosaminide ≥99% (TLC)

Sigma-Aldrich

N9376

4-Nitrophenyl N-acetyl-β-D-glucosaminide

assay

≥99.0% (TLC)

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥99% (TLC)

solubility

H2O: 0.1 g/mL, clear, faintly yellow

solubility

H2O: soluble 100 mg/mL, clear

solubility

water: 50 mg/mL, clear to very slightly hazy

solubility

water: 5 mg/mL, clear, colorless to very faintly yellow

suitability

suitable as substrate for β-glucuronidase test

suitability

-

suitability

-

suitability

-

Quality Level

200

Quality Level

200

Quality Level

300

Quality Level

300

form

powder or crystals

form

powder

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

Chromogenic substrate for β-glucuronidase (GUS) gene detection.

Application

4-Nitrophenyl β-D-glucuronide has been used for determining the β-glucuronidase activity in urine samples,[1] β-glucuronidase activity of bacteria in caecum content digesta[2] and bovine liver.[3] It has also been used to study the inhibitory effect of Phyllanthus amarus extracts on β-glucuronidase.[4]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCN7534
BCCL8087
BCCL2707
BCCH4350
BCCG4124

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
El-Arab AME, et al.
BMC Complementary and Alternative Medicine, 6(1), 6-6 (2006)
Effect of tobacco smoking on albumin concentration and beta-glucuronidase activity in urine of smelters
Bizonn A, et al.
Przegla?d Lekarski, 71(11), 581-584 (2014)
Synthesis of Glycaro-1, 5-lactams and Tetrahydrotetrazolopyridine-5-carboxylates: Inhibitors of beta-D-Glucuronidase and alpha-L-Iduronidase
Pabba J, et al.
Helvetica Chimica Acta, 89(4), 635-666 (2006)
E E Guibert et al.
Experientia, 39(5), 527-528 (1983-05-15)
The effect of spironolactone (SP) on p-nitrophenol (PNP) glucuronidation was studied in isolated rat hepatocytes with appropriate viability conditions. A significant increase of protein concentration and PNP glucuronidation was found in the hepatocytes from SP-treated rats. Increased enzyme activity apparently
C Y Ng et al.
The Journal of pharmacology and experimental therapeutics, 295(2), 830-835 (2000-10-25)
Congestive heart failure has been shown to affect oxidative drug metabolism, however, there has been little study of its effects on drug conjugation. Using the isolated perfused livers from rats with right ventricular failure (RVF) due to pulmonary artery constriction
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service