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76275

PBFI-AM

suitable for fluorescence, ≥98.0% (HPCE)

Synonym(s):

Potassium indicator PBFI-AM, Potassium-binding benzofuran isophthalate-AM

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Pack SizeSKUAvailabilityPrice
1 mg

Available to ship TODAYfromMILWAUKEE

$1,020.00
$510.00

About This Item

Empirical Formula (Hill Notation):
C58H62N2O24
CAS Number:
Molecular Weight:
1171.11
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:

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Quality Level

assay

≥98.0% (HPCE)

form

powder

solubility

DMSO: soluble, methanol: soluble

fluorescence

λex 334 nm; λem 525 nm (with Na), λex 370 nm; λem 540 nm in methanol

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

COc1cc2cc(oc2cc1N3CCOCCOCCN(CCOCCOCC3)c4cc5oc(cc5cc4OC)-c6ccc(cc6C(=O)OCOC(C)=O)C(=O)OCOC(C)=O)-c7ccc(cc7C(=O)OCOC(C)=O)C(=O)OCOC(C)=O

InChI

1S/C58H62N2O24/c1-35(61)75-31-79-55(65)39-7-9-43(45(23-39)57(67)81-33-77-37(3)63)51-25-41-27-53(69-5)47(29-49(41)83-51)59-11-15-71-19-21-73-17-13-60(14-18-74-22-20-72-16-12-59)48-30-50-42(28-54(48)70-6)26-52(84-50)44-10-8-40(56(66)80-32-76-36(2)62)24-46(44)58(68)82-34-78-38(4)64/h7-10,23-30H,11-22,31-34H2,1-6H3

InChI key

AUKRBWNSOWVABU-UHFFFAOYSA-N

Application

suitable for the detection of K+

Other Notes

Cell permeant deriv. of fluorescent indicator for mitochondrial potassium[1][2]

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This Item
2517651.051041.05109
suitability

suitable for fluorescence

suitability

-

suitability

-

suitability

-

fluorescence

λex 334 nm; λem 525 nm (with Na), λex 370 nm; λem 540 nm in methanol

fluorescence

λex ~560 nm, λem ~575 nm

fluorescence

-

fluorescence

-

solubility

DMSO: soluble, methanol: soluble

solubility

-

solubility

1600 g/L

solubility

1600 g/L

form

powder

form

solution

form

solid

form

solid

Quality Level

100

Quality Level

100

Quality Level

300

Quality Level

100

assay

≥98.0% (HPCE)

assay

≥98% (HPLC)

assay

≥99.0% (alkalimetric)

assay

99.99%


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Fluorescence lifetime measurement is advantageous over intensity-based measurements. Applications include fluorescence lifetime assays, sensing and FLI.

Nitric oxide (NO) as a signal transporter in neurons, endothelial cells and in the immune system.


Yu-Chan Wang et al.
Journal of neuroinflammation, 12, 246-246 (2015-12-31)
Acid-sensing ion channels (ASICs) are cation channels which were activated by extracellular acidosis and involved in various physiological and pathological processes in the nervous system. Inflammasome is a key component of the innate immune response in host against harmful and
P. Jezek et al.
The Journal of Biological Chemistry, 264, 10522-10522 (1990)
J P Zoeteweij et al.
The Biochemical journal, 299 ( Pt 2), 539-543 (1994-04-15)
In isolated rat hepatocytes a sustained high increase in intracellular free Ca2+ ([Ca2+]i), induced by extracellular ATP, is associated with mitochondrial dysfunction and cell death. The Ca(2+)-induced effects are Pi-dependent and less severe when the intracellular K+ content is low.



Global Trade Item Number

SKUGTIN
76275-1MG04061823356398

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